Cystic nephroma pathophysiology: Difference between revisions
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{{CMG}}; {{AE}} {{SC}} | {{CMG}}; {{AE}} {{SC}} | ||
==Overview== | ==Overview== | ||
===Pathologic diagnosis=== | |||
[[Image:Cystic nephroma high mag.jpg|thumb|right|250px|High magnification micrograph of a '''cystic nephroma''' showing the characteristic [[simple epithelium]] with hobnail morphology, and the [[ovary|ovarian]]-like [[stroma of ovary|stroma]]. [[H&E stain]].]] | |||
The characteristics of cystic nephromas are: | |||
*[[Cyst]]s lined by a simple epithelium with a ''hobnail morphology'', i.e. the nuclei of the cyst lining epithelium bulges into the lumen of the cysts, | |||
*[[w:ovary|Ovarian]]-like [[stroma (animal tissue)|stroma]] that has a: | |||
**[[w:spindle cell|Spindle cell]] morphology, and has a | |||
**Basophilic [[w:cytoplasm|cytoplasm]]. | |||
Cystic nephromas have an immunostaining pattern like ovarian stroma; they are positive for: | |||
*[[w:Estrogen receptor|Estrogen receptor (ER)]], | |||
*[[w:Progesterone receptor|Progesterone receptor (PR)]] and | |||
*[[w:CD10|CD10]]. | |||
Revision as of 18:00, 29 October 2015
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Cystic nephroma Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
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Cystic nephroma pathophysiology On the Web |
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American Roentgen Ray Society Images of Cystic nephroma pathophysiology |
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Risk calculators and risk factors for Cystic nephroma pathophysiology |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Shanshan Cen, M.D. [2]
Overview
Pathologic diagnosis
The characteristics of cystic nephromas are:
- Cysts lined by a simple epithelium with a hobnail morphology, i.e. the nuclei of the cyst lining epithelium bulges into the lumen of the cysts,
- Ovarian-like stroma that has a:
- Spindle cell morphology, and has a
- Basophilic cytoplasm.
Cystic nephromas have an immunostaining pattern like ovarian stroma; they are positive for: