Renal oncocytoma pathophysiology: Difference between revisions
Jump to navigation
Jump to search
Shanshan Cen (talk | contribs) |
Shanshan Cen (talk | contribs) |
||
Line 12: | Line 12: | ||
==Microscopic Pathology== | ==Microscopic Pathology== | ||
* An epithelial tumor composed of oncocytes, large [[eosinophilic]] cells having small, round, benign-appearing [[nuclei]] with large [[nucleoli]] | * An epithelial tumor composed of oncocytes, large [[eosinophilic]] cells having small, round, benign-appearing [[nuclei]] with large [[nucleoli]] and excessive amounts of [[mitochondria]].<ref name="pmid2028856">{{cite journal |vauthors=Palmer WE, Chew FS |title=Renal oncocytoma |journal=AJR Am J Roentgenol |volume=156 |issue=6 |pages=1144 |year=1991 |pmid=2028856 |doi=10.2214/ajr.156.6.2028856 |url=http://www.ajronline.org/doi/abs/10.2214/ajr.156.6.2028856}}</ref> | ||
==References== | ==References== |
Revision as of 18:35, 29 October 2015
Renal oncocytoma Microchapters |
Diagnosis |
---|
Treatment |
Case Studies |
Renal oncocytoma pathophysiology On the Web |
American Roentgen Ray Society Images of Renal oncocytoma pathophysiology |
Risk calculators and risk factors for Renal oncocytoma pathophysiology |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Shanshan Cen, M.D. [2]
Overview
On gross pathology, tan or mahogany brown, well circumscribed tumor, and central scar are characteristic findings of renal oncocytoma. On microscopic histopathological analysis, oncocytes and large eosinophilic cells are characteristic findings of renal oncocytoma.[1]
Pathogenesis
- Renal oncocytoma is thought to arise from the intercalated cells of collecting ducts of the kidney.[2]
Gross Pathology
- The tumors are tan or mahogany brown, well circumscribed, and contain a central scar. They may achieve a large size (up to 12 cm in diameter).[2]
Microscopic Pathology
- An epithelial tumor composed of oncocytes, large eosinophilic cells having small, round, benign-appearing nuclei with large nucleoli and excessive amounts of mitochondria.[1]
References
- ↑ 1.0 1.1 Palmer WE, Chew FS (1991). "Renal oncocytoma". AJR Am J Roentgenol. 156 (6): 1144. doi:10.2214/ajr.156.6.2028856. PMID 2028856.
- ↑ 2.0 2.1 Velasquez G, Glass TA, D'Souza VJ, Formanek AG (1984). "Multiple oncocytomas and renal carcinoma". AJR Am J Roentgenol. 142 (1): 123–4. doi:10.2214/ajr.142.1.123. PMID 6606945.