Renal oncocytoma pathophysiology: Difference between revisions
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==Gross Pathology== | ==Gross Pathology== | ||
* The [[tumors]] are tan or mahogany brown, well circumscribed, and contain a central scar. They may achieve a large size (up to 12 cm in diameter).<ref name="pmid6606945">{{cite journal |vauthors=Velasquez G, Glass TA, D'Souza VJ, Formanek AG |title=Multiple oncocytomas and renal carcinoma |journal=AJR Am J Roentgenol |volume=142 |issue=1 |pages=123–4 |year=1984 |pmid=6606945 |doi=10.2214/ajr.142.1.123 |url=http://www.ajronline.org/doi/abs/10.2214/ajr.142.1.123}}</ref> | * The [[tumors]] are tan or mahogany brown, well circumscribed, and contain a central scar. They may achieve a large size (up to 12 cm in diameter).<ref name="pmid6606945">{{cite journal |vauthors=Velasquez G, Glass TA, D'Souza VJ, Formanek AG |title=Multiple oncocytomas and renal carcinoma |journal=AJR Am J Roentgenol |volume=142 |issue=1 |pages=123–4 |year=1984 |pmid=6606945 |doi=10.2214/ajr.142.1.123 |url=http://www.ajronline.org/doi/abs/10.2214/ajr.142.1.123}}</ref> | ||
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Renal oncocytoma1.jpg|Renal oncocytoma<ref>Renla oncocytoma. Libre Pathology 2015. http://librepathology.org/wiki/index.php/Renal_oncocytoma Accessed on October, 29 2015 </ref> | |||
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==Microscopic Pathology== | ==Microscopic Pathology== | ||
Revision as of 19:02, 29 October 2015
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Shanshan Cen, M.D. [2]
Overview
On gross pathology, tan or mahogany brown, well circumscribed tumor, and central scar are characteristic findings of renal oncocytoma. On microscopic histopathological analysis, oncocytes and large eosinophilic cells are characteristic findings of renal oncocytoma.[1]
Pathogenesis
- Renal oncocytoma is thought to arise from the intercalated cells of collecting ducts of the kidney.[2]
Gross Pathology
- The tumors are tan or mahogany brown, well circumscribed, and contain a central scar. They may achieve a large size (up to 12 cm in diameter).[2]
-
![Renal oncocytoma[3]](/images/1/19/Renal_oncocytoma1.jpg)
Renal oncocytoma[3]
![Renal oncocytoma[3]](/index.php/File:Renal_oncocytoma1.jpg)
Microscopic Pathology
- An epithelial tumor composed of oncocytes, large eosinophilic cells having small, round, benign-appearing nuclei with large nucleoli and excessive amounts of mitochondria.[1]
References
- ↑ 1.0 1.1 Palmer WE, Chew FS (1991). "Renal oncocytoma". AJR Am J Roentgenol. 156 (6): 1144. doi:10.2214/ajr.156.6.2028856. PMID 2028856.
- ↑ 2.0 2.1 Velasquez G, Glass TA, D'Souza VJ, Formanek AG (1984). "Multiple oncocytomas and renal carcinoma". AJR Am J Roentgenol. 142 (1): 123–4. doi:10.2214/ajr.142.1.123. PMID 6606945.
- ↑ Renla oncocytoma. Libre Pathology 2015. http://librepathology.org/wiki/index.php/Renal_oncocytoma Accessed on October, 29 2015