Essential thrombocytosis overview: Difference between revisions
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==Overview== | ==Overview== | ||
'''Primary''' or Essential thrombocytosis''' '''(ET)''' is a rare hematologic disorder characterized by overproduction of platelets in the absence of an underlying disease. The disease, also called as Epstein-Goedel syndrome was first described by pathologists Emil Epstein and Alfred Goedel in the year 1934. Platelets are non-nucleated fragments of cytoplasm that aid in blood clotting by forming a platelet plug sealing off the site of injury. Normal platelet counts usually range from 150,000-450,000 platelets/μL of blood. Thrombocytosis is when the counts stay consistently higher at more than 450,000 platelets/μL of blood and Thrombocytopenia is when the counts are consistently lower than 150,000 platelets/μL of blood. ET is grouped under the myeloproliferative disorders along with | '''Primary''' or Essential thrombocytosis''' '''(ET)''' is a rare hematologic disorder characterized by overproduction of platelets in the absence of an underlying disease. The disease, also called as Epstein-Goedel syndrome was first described by pathologists Emil Epstein and Alfred Goedel in the year 1934. Platelets are non-nucleated fragments of cytoplasm that aid in blood clotting by forming a platelet plug sealing off the site of injury. Normal platelet counts usually range from 150,000-450,000 platelets/μL of blood. Thrombocytosis is when the counts stay consistently higher at more than 450,000 platelets/μL of blood and Thrombocytopenia is when the counts are consistently lower than 150,000 platelets/μL of blood. ET is grouped under the myeloproliferative disorders along with polycythemia vera, chronic myeloid leukaemia and myelofibrosis. Rarely the disease progresses to acute myeloid leukemia('''AML''') | ||
Revision as of 13:29, 30 October 2015
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Essential thrombocytosis Microchapters |
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Differentiating Essential thrombocytosis from other Diseases |
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Diagnosis |
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Treatment |
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Essential thrombocytosis overview On the Web |
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American Roentgen Ray Society Images of Essential thrombocytosis overview |
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Risk calculators and risk factors for Essential thrombocytosis overview |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Primary or Essential thrombocytosis (ET) is a rare hematologic disorder characterized by overproduction of platelets in the absence of an underlying disease. The disease, also called as Epstein-Goedel syndrome was first described by pathologists Emil Epstein and Alfred Goedel in the year 1934. Platelets are non-nucleated fragments of cytoplasm that aid in blood clotting by forming a platelet plug sealing off the site of injury. Normal platelet counts usually range from 150,000-450,000 platelets/μL of blood. Thrombocytosis is when the counts stay consistently higher at more than 450,000 platelets/μL of blood and Thrombocytopenia is when the counts are consistently lower than 150,000 platelets/μL of blood. ET is grouped under the myeloproliferative disorders along with polycythemia vera, chronic myeloid leukaemia and myelofibrosis. Rarely the disease progresses to acute myeloid leukemia(AML)