Sandbox:DDx HEENT: Difference between revisions

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* 40-60 yo women
* May have diarrhea, flushing, and pruritis
* May have bone pain or respiratory symptoms
* MEN2 (pheochromocytoma and hyperparathyroidism symptoms)
 
* Thyroid nodule
* Painless thyroid nodule
* Neck lymphadenopathy
 
* RET proto-oncogene
 
* Invasion of capsule and surrounding parenchyma/blood vessels on true cut biopsy
* Thick calcified capsule present
* Follicular/solid growth pattern with Hürthle cells, nuclear atypia, and increased mitotic activity on FNA
 
 
* Hypoechoic solid solitary mass on U/S
* Uninodular lymph node involvement
* RAS oncogene activation
* PAX8-PPAR gamma 1 genes rearrangement

Revision as of 16:47, 1 November 2015

  • May have diarrhea, flushing, and pruritis
  • MEN2 (pheochromocytoma and hyperparathyroidism symptoms)
  • Thyroid nodule
  • Neck lymphadenopathy
  • RET proto-oncogene
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