Sandbox:DDx HEENT: Difference between revisions

Jump to navigation Jump to search
No edit summary
No edit summary
Line 10: Line 10:
* Elevated CEA
* Elevated CEA


* Multiple hypoechoegenic lesions on U/s
* Lymph node calcifications
* Liver metastasis
* Nested cellular pattern separated by delicate vascular septa  
* Nested cellular pattern separated by delicate vascular septa  
* Polygonal cells, round nuclie with coarse chromatin, granular cytoplasm, surrounded by amyloid deposits
* Polygonal cells, round nuclie with coarse chromatin, granular cytoplasm, surrounded by amyloid deposits

Revision as of 17:04, 1 November 2015

  • 35 yo women
  • May have diarrhea, flushing, and pruritis
  • MEN2 (pheochromocytoma and hyperparathyroidism symptoms)
  • Painless thyroid nodule
  • Neck lymphadenopathy
  • Elevated calcitonin
  • Elevated chromogranin
  • Elevated CEA
  • Multiple hypoechoegenic lesions on U/s
  • Lymph node calcifications
  • Liver metastasis
  • Nested cellular pattern separated by delicate vascular septa
  • Polygonal cells, round nuclie with coarse chromatin, granular cytoplasm, surrounded by amyloid deposits
  • Vascular stroma with hemorrhage, edema, and coarse calcification
  • C-cell hyperplasia may be present


  • RET proto-oncogene