Sandbox:DDx HEENT: Difference between revisions
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Fatigue, weight gain, cold intolerance, constipation, myopathy, depression, menorrhagia, and infertility | * 15-30 yo women | ||
* Fatigue, weight gain, cold intolerance, constipation, myopathy, depression, menorrhagia, and infertility | |||
Nontender mild neck swelling | * Nontender mild neck swelling | ||
Puffy face, bradycardia, and dry skin | * Puffy face, bradycardia, and dry skin | ||
Decreased T3/T4 and increased TSH | * Decreased T3/T4 and increased TSH | ||
Anti-thyroid peroxidase antibodies | * Anti-thyroid peroxidase antibodies | ||
* Elevated cholesterol levels | |||
* Hypoechoic thyroid gland with coarse or "micronodular" echotexture on U/S | |||
* Increased vascularity of the gland | |||
* Extensive T cell lymphocytic infiltrate | |||
* Nuclear clearing | |||
* Germinal center formation | |||
* Hürthle cells and giant cells | |||
* Fibrosis | |||
* HLA-DR5 | |||
* CTLA4 | |||
Revision as of 21:37, 1 November 2015
- 15-30 yo women
- Fatigue, weight gain, cold intolerance, constipation, myopathy, depression, menorrhagia, and infertility
- Nontender mild neck swelling
- Puffy face, bradycardia, and dry skin
- Decreased T3/T4 and increased TSH
- Anti-thyroid peroxidase antibodies
- Elevated cholesterol levels
- Hypoechoic thyroid gland with coarse or "micronodular" echotexture on U/S
- Increased vascularity of the gland
- Extensive T cell lymphocytic infiltrate
- Nuclear clearing
- Germinal center formation
- Hürthle cells and giant cells
- Fibrosis
- HLA-DR5
- CTLA4