Sandbox:DDx HEENT: Difference between revisions

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* 35-50 yo women
* Could be clinically silent-cold nodule
* Painless nodular enlargement in the neck
* Hyperthyroidism symptoms-hot nodule
* Euthyroid state
* Solitary, spherical, encapsulated, and well demarcated from the surrounding parenchyma
 
* Areas of hemorrhage, fibrosis, calcification, and cystic changes
* Iso-hyperechoic mass with alarge cystic component on U/S
* Surrounding hypoechoic halo
* Spongelike/honeycomb pattern with eggshell coarse calcifications
* Intranodular vascularity
 
* Heterogeneous iodine uptake on thyroid scan
 
* Follicles of variable size
* microfollicular architecture
* Unencapsulated 
* No nuclear features suggestive of malignancy
 
* TG-gene
* TPO-gene
* SLC5A5 gene
* SLC26A4 gene
* TSH-R-gene
* DEHAL-1 gene
* DUOX2 gene

Revision as of 22:41, 1 November 2015

  • Could be clinically silent-cold nodule
  • Hyperthyroidism symptoms-hot nodule
  • Solitary, spherical, encapsulated, and well demarcated from the surrounding parenchyma
  • Areas of hemorrhage, fibrosis, calcification, and cystic changes
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