Waldenström's macroglobulinemia pathophysiology: Difference between revisions
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{{Waldenström's macroglobulinemia}} | {{Waldenström's macroglobulinemia}} | ||
{{CMG}} | {{CMG}} {{AE}}{{MGS}} | ||
==Overview== | ==Overview== | ||
== Pathogenesis == | == Pathogenesis == |
Revision as of 16:20, 3 November 2015
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Mirdula Sharma, MBBS [2]
Overview
Pathogenesis
It is due to the effects of the IgM paraprotein, which may cause autoimmune phenomenon or cryoglobulinemia. Other symptoms of WM are due to the hyperviscosity syndrome, which is present in 6-20% of patients.This is attributed to the IgM monoclonal protein increasing the viscosity of the blood.