Sandbox: DDx Kidney mass: Difference between revisions
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* Fluid filled saccular expansions of glomerular capsule and renal tubule | * Fluid filled saccular expansions of glomerular capsule and renal tubule | ||
* Lined by cuboidal epithelium | * Lined by cuboidal epithelium | ||
* Disconnection of the glomerular capsule | * Disconnection of the glomerular capsule | ||
Revision as of 13:22, 5 November 2015
- 30 yo patients
- Abdominal, flank, or back pain
- Hematuria, hypertenstion, intracranial hemorrhage
- ESRD at age 60
- Progressive decrease in GFR
- Elevated creatinine and BUN
- Multiple bilateral renal cysts on U/S
- Anechoic with well-defined imperceptible walls
- Palpable, bilateral flank masses
- Nodular hepatomegaly
- Fluid filled saccular expansions of glomerular capsule and renal tubule
- Lined by cuboidal epithelium
- Disconnection of the glomerular capsule
- Polyps and papillary projections
- Areas of tubular atrophy, interstitial fibrosis, and global sclerosis are present between cyst
- PKD1 gene at chromosome 16
- PKD2 gene at chromosome 4
Nonmalignant causes
acquired cystic kidney disease cystic renal dysplasia glomerulocystic kidney medullary sponge kidney mesothelial cysts nephronophthisis simple cysts