Waldenström's macroglobulinemia causes: Difference between revisions
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The most common causes of Waldenström's macroglobulinemia is | The most common causes of Waldenström's macroglobulinemia is somatic mutation in MYD88 (90% of patients) and a somatic mutation in CXCR4 (27% of patients).<ref name=wiki> Waldenström's macroglobulinemia. Wikipedia (2015). https://en.wikipedia.org/wiki/Waldenström%27s_macroglobulinemia#cite_note-19 Accessed on November 6, 2015</ref> | ||
Less common causes of Waldenström's macroglobulinemia include: | |||
*Chromosomal abnormalities: deletions of 6q23 and 13q14, and gains of 3q13-q28, 6p and 18q | |||
*Environmental factors including exposure to farming, pesticides, wood dust, and organic solvents | |||
==References== | ==References== | ||
Revision as of 16:06, 6 November 2015
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The most common causes of Waldenström's macroglobulinemia is somatic mutation in MYD88 (90% of patients) and a somatic mutation in CXCR4 (27% of patients).[1]
Less common causes of Waldenström's macroglobulinemia include:
- Chromosomal abnormalities: deletions of 6q23 and 13q14, and gains of 3q13-q28, 6p and 18q
- Environmental factors including exposure to farming, pesticides, wood dust, and organic solvents
References
- ↑ Waldenström's macroglobulinemia. Wikipedia (2015). https://en.wikipedia.org/wiki/Waldenström%27s_macroglobulinemia#cite_note-19 Accessed on November 6, 2015