Polycythemia vera causes: Difference between revisions
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Polycythemia vera is caused by a mutation in the ''[[JAK2]]'' kinase (V617F) gene.<ref>{{cite journal | author=Baxter EJ, Scott LM, Campbell PJ, East C, Fourouclas N, Swanton S, Vassiliou GS, Bench AJ, Boyd EM, Curtin N, Scott MA, Erber WN, Green AR | title=Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders | journal=Lancet | year=2005 | pages=1054-61 | volume=365 | issue=9464 | id=PMID 15781101}}</ref> | Polycythemia vera is caused by a mutation in the ''[[JAK2]]'' kinase (V617F) gene.<ref>{{cite journal | author=Baxter EJ, Scott LM, Campbell PJ, East C, Fourouclas N, Swanton S, Vassiliou GS, Bench AJ, Boyd EM, Curtin N, Scott MA, Erber WN, Green AR | title=Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders | journal=Lancet | year=2005 | pages=1054-61 | volume=365 | issue=9464 | id=PMID 15781101}}</ref> | ||
==Common Causes== | ==Common Causes== | ||
Polycythemia vera is caused by a mutation in the ''[[JAK2]]'' kinase (V617F) gene.<ref>{{cite journal | author=Baxter EJ, Scott LM, Campbell PJ, East C, Fourouclas N, Swanton S, Vassiliou GS, Bench AJ, Boyd EM, Curtin N, Scott MA, Erber WN, Green AR | title=Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders | journal=Lancet | year=2005 | pages=1054-61 | volume=365 | issue=9464 | id=PMID 15781101}}</ref>==References== | Polycythemia vera is caused by a mutation in the ''[[JAK2]]'' kinase (V617F) gene.<ref>{{cite journal | author=Baxter EJ, Scott LM, Campbell PJ, East C, Fourouclas N, Swanton S, Vassiliou GS, Bench AJ, Boyd EM, Curtin N, Scott MA, Erber WN, Green AR | title=Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders | journal=Lancet | year=2005 | pages=1054-61 | volume=365 | issue=9464 | id=PMID 15781101}}</ref> | ||
==References== | |||
{{Reflist|2}} | {{Reflist|2}} | ||
{{Hematology}} | {{Hematology}} | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Mohamad Alkateb, MBBCh [2]
Overview
Polycythemia vera is caused by a mutation in the JAK2 kinase (V617F) gene.[1]
Common Causes
Polycythemia vera is caused by a mutation in the JAK2 kinase (V617F) gene.[2]
References
- ↑ Baxter EJ, Scott LM, Campbell PJ, East C, Fourouclas N, Swanton S, Vassiliou GS, Bench AJ, Boyd EM, Curtin N, Scott MA, Erber WN, Green AR (2005). "Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders". Lancet. 365 (9464): 1054–61. PMID 15781101.
- ↑ Baxter EJ, Scott LM, Campbell PJ, East C, Fourouclas N, Swanton S, Vassiliou GS, Bench AJ, Boyd EM, Curtin N, Scott MA, Erber WN, Green AR (2005). "Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders". Lancet. 365 (9464): 1054–61. PMID 15781101.