Waldenström's macroglobulinemia history and symptoms: Difference between revisions

Jump to navigation Jump to search
← Older editNewer edit →
VisualWikitext
Jyostna Chouturi (talk | contribs)
nocaptcha
9,554 edits
No edit summary
Mirdula Sharma (talk | contribs)
nocaptcha
771 edits
Line 4: Line 4:
==Overview==
==Overview==
==History and Symptoms==
==History and Symptoms==
Symptoms of WM include
Patients with WM may present with various symptoms.
* [[Weakness]]
*Approximately 30% of the patients are asymptomatic (smoldering WM).
* [[fatigue (physical)|Fatigue]]
*Anemia with mean hemoglobin less than 10 g/dL - fatigue
* [[Weight loss]]
*Bone marrow infiltration: cause anemia & pancytopenia
* [[Loss of vision]]
*Extramedullary infiltration - hepatomegaly, splenomegaly, lymphadenopathy
* [[Headache]]
*Hyperviscosity - oronasal bleeding, retinal hemorrhage with blurring or loss of vision, headache, vertigo, ataxia
* [[Stroke]]
*IgM monoclonal proteins - peripheral neuropathy
* [[Coma]]<ref name="Owen">{{cite journal | author=Owen RG, Barrans SL, Richards SJ, O'Connor SJ, Child JA, Parapia LA, Morgan GJ, Jack AS | title=Waldenstrom macroglobulinemia. Development of diagnostic criteria and identification of prognostic factors | journal=Am J Clin Pathol | year=2001 | pages=420-8 | volume=116 | issue=3  | id=PMID 11554171}}</ref><ref name="SanMiguel">{{cite journal | author=San Miguel JF, Vidriales MB, Ocio E, Mateo G, Sanchez-Guijo F, Sanchez ML, Escribano L, Barez A, Moro MJ, Hernandez J, Aguilera C, Cuello R, Garcia-Frade J, Lopez R, Portero J, Orfao A | title=Immunophenotypic analysis of Waldenstrom's macroglobulinemia | journal=Semin Oncol | year=2003 | pages=187-95 | volume=30 | issue=2  | id=PMID 12720134}}</ref><ref name="Ghobrial">{{cite journal | author=Ghobrial IM, Witzig TE | title=Waldenstrom macroglobulinemia | journal=Curr Treat Options Oncol | year=2004 | pages=239-47 | volume=5 | issue=3  | id=PMID 15115652}}</ref>
* Chronic oozing of blood from the nose and gums.<ref name="Kyle1988">{{cite book | author =Kyle RA  | year = 1998 | title = Internal Medicine | chapter = Chapter 94: Multiple Myeloma and the Dysproteinemias | editor = Stein JH | edition = 5th ed. | publisher = C.V.Mosby | location = New York | id = ISBN 0815186983 }}</ref>


==References==
==References==

Revision as of 20:48, 6 November 2015

Waldenström's macroglobulinemia Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Waldenström's macroglobulinemia from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Study of Choice

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

Bone Marrow Aspiration and Biopsy

Electrophoresis and Immunofixation

Chest X Ray

CT

MRI

Echocardiography or Ultrasound

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Waldenström's macroglobulinemia history and symptoms On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Waldenström's macroglobulinemia history and symptoms

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Waldenström's macroglobulinemia history and symptoms

CDC on Waldenström's macroglobulinemia history and symptoms

Waldenström's macroglobulinemia history and symptoms in the news

Blogs on Waldenström's macroglobulinemia history and symptoms

Directions to Hospitals Treating Waldenström's macroglobulinemia

Risk calculators and risk factors for Waldenström's macroglobulinemia history and symptoms

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

History and Symptoms

Patients with WM may present with various symptoms.

  • Approximately 30% of the patients are asymptomatic (smoldering WM).
  • Anemia with mean hemoglobin less than 10 g/dL - fatigue
  • Bone marrow infiltration: cause anemia & pancytopenia
  • Extramedullary infiltration - hepatomegaly, splenomegaly, lymphadenopathy
  • Hyperviscosity - oronasal bleeding, retinal hemorrhage with blurring or loss of vision, headache, vertigo, ataxia
  • IgM monoclonal proteins - peripheral neuropathy

References

Template:WH Template:WS

Retrieved from "https://www.wikidoc.org/index.php?title=Waldenström%27s_macroglobulinemia_history_and_symptoms&oldid=1184530"