Sandbox: DDx Kidney mass: Difference between revisions

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* 40 yo patients 
* Present at birth
* Haematuria


* Abdominal pain
* Palpable abdominal mass
* Hematuria
* Polycythemia symptoms


* Palpable mass
* Fetal hypercalcaemia


* Arrangement of monotonous small blue embryonal epithelial cells
* Connective tissue growing between nephrons replacing most of the renal parenchyma
* Acinar, tubular, or sheetlike configuration
* Cellular clusters of spindle cells
* Psammoma bodies
* Mild nuclear pleomorphism
* Vimentin, pancytokeratin and cytokeratin-19
* Increased mitotic activity
* No blastema
 
* Antenatal U/S
* Well-defined mass with low-level homogeneous echoes
* Concentric echogenic and hypoechoic rings
* Increased vasculairty
* Polyhydramnios


* Hyperattenuating heterogeneous mass on CT
* Unenhanced large hypovascular mass
* Frequent foci of hemorrhage and necrosis
* Calcification





Revision as of 13:52, 9 November 2015

  • Present at birth
  • Haematuria
  • Palpable abdominal mass
  • Fetal hypercalcaemia
  • Connective tissue growing between nephrons replacing most of the renal parenchyma
  • Cellular clusters of spindle cells
  • Mild nuclear pleomorphism
  • Increased mitotic activity
  • No blastema
  • Antenatal U/S
  • Well-defined mass with low-level homogeneous echoes
  • Concentric echogenic and hypoechoic rings
  • Increased vasculairty
  • Polyhydramnios



Nonmalignant causes

anaplastic sarcoma clear cell sarcoma mesoblastic nephroma metanephric stromal tumor nephroblastomatosis / nephrogenic rests neuroblastoma oncocytoid carcinoma after neuroblastoma ossifying