Sandbox: DDx Kidney mass: Difference between revisions

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* 10-30 yo sickle cell trait patients
* May have gross hematuria, back/flank pain, weight loss, and fever


* Present at birth
* Palpable renal mass  
* Haematuria
* Lymphadenopathy
 
* Palpable abdominal mass
 
* Fetal hypercalcaemia
 
* Connective tissue growing between nephrons replacing most of the renal parenchyma
* Cellular clusters of spindle cells
* Mild nuclear pleomorphism
* Increased mitotic activity
* No blastema
 
* Antenatal U/S
* Well-defined mass with low-level homogeneous echoes
* Concentric echogenic and hypoechoic rings
* Increased vasculairty
* Polyhydramnios
 
 
* t(12;15)
* ETV6-NTRK3 gene fusion
 
 


* Centrally located infiltrative mass invading the renal sinus
* Peripheral caliectasis
* Smaller peripheral satellite nodules
* Heterogeneous enhancement on CT
* Heterogeneous echotexture on US
==Nonmalignant causes==
==Nonmalignant causes==
anaplastic sarcoma clear cell sarcoma mesoblastic nephroma metanephric stromal tumor nephroblastomatosis / nephrogenic rests neuroblastoma oncocytoid carcinoma after neuroblastoma ossifying
anaplastic sarcoma clear cell sarcoma mesoblastic nephroma metanephric stromal tumor nephroblastomatosis / nephrogenic rests neuroblastoma oncocytoid carcinoma after neuroblastoma ossifying

Revision as of 14:14, 9 November 2015

  • 10-30 yo sickle cell trait patients
  • May have gross hematuria, back/flank pain, weight loss, and fever
  • Palpable renal mass
  • Lymphadenopathy
  • Centrally located infiltrative mass invading the renal sinus
  • Peripheral caliectasis
  • Smaller peripheral satellite nodules
  • Heterogeneous enhancement on CT
  • Heterogeneous echotexture on US

Nonmalignant causes

anaplastic sarcoma clear cell sarcoma mesoblastic nephroma metanephric stromal tumor nephroblastomatosis / nephrogenic rests neuroblastoma oncocytoid carcinoma after neuroblastoma ossifying

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