Sandbox: DDx Kidney mass: Difference between revisions

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60-70 male patients
* 60-70 male patients
von Hippel-Lindau syndrome
* von Hippel-Lindau syndrome




Polygonal cells, clear cytoplasm, and a central nucleus
* Polygonal cells, clear cytoplasm, and a central nucleus
Delicate branching vasculature
* Delicate branching vasculature
"Chicken wire-like" vasculature
* "Chicken wire-like" vasculature
Hyaline bodies common
* Hyaline bodies common




Chromosome 3 mutation
* Chromosome 3 mutation
VHL gene mutation  
* VHL gene mutation  
Gain of chromosome 5
* Gain of chromosome 5


==Nonmalignant causes==
==Nonmalignant causes==
anaplastic sarcoma clear cell sarcoma mesoblastic nephroma metanephric stromal tumor nephroblastomatosis / nephrogenic rests neuroblastoma oncocytoid carcinoma after neuroblastoma ossifying
anaplastic sarcoma clear cell sarcoma mesoblastic nephroma metanephric stromal tumor nephroblastomatosis / nephrogenic rests neuroblastoma oncocytoid carcinoma after neuroblastoma ossifying

Revision as of 15:52, 9 November 2015

  • 60-70 male patients
  • von Hippel-Lindau syndrome


  • Polygonal cells, clear cytoplasm, and a central nucleus
  • Delicate branching vasculature
  • "Chicken wire-like" vasculature
  • Hyaline bodies common


  • Chromosome 3 mutation
  • VHL gene mutation
  • Gain of chromosome 5

Nonmalignant causes

anaplastic sarcoma clear cell sarcoma mesoblastic nephroma metanephric stromal tumor nephroblastomatosis / nephrogenic rests neuroblastoma oncocytoid carcinoma after neuroblastoma ossifying