Sandbox: DDx Kidney mass: Difference between revisions

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* 40-50 yo patients
* May have refractory hypertension, palpitations, headache, diaphoresis, anxiety,  weight loss, and flank pain   
* May have refractory hypertension, palpitations, headache, diaphoresis, anxiety,  weight loss, and flank pain   
* MEN, von Hippel–Lindau disease, tuberous sclerosis, or neurofibromatosis
* MEN, von Hippel–Lindau disease, tuberous sclerosis, or neurofibromatosis

Revision as of 16:53, 9 November 2015

  • 40-50 yo patients
  • May have refractory hypertension, palpitations, headache, diaphoresis, anxiety, weight loss, and flank pain
  • MEN, von Hippel–Lindau disease, tuberous sclerosis, or neurofibromatosis
  • Pallor
  • Tachycardia
  • Elevated serum catecholamines and metanephrines
  • Large, heterogeneous mass on CT
  • Areas of necrosis and cystic change
  • on CT
  • VHL, RET, NF1SDHB and SDHD gene mutation

Nonmalignant causes

anaplastic sarcoma clear cell sarcoma mesoblastic nephroma metanephric stromal tumor nephroblastomatosis / nephrogenic rests neuroblastoma oncocytoid carcinoma after neuroblastoma ossifying