Sandbox: maria: Difference between revisions
Jump to navigation
Jump to search
No edit summary |
No edit summary |
||
| Line 4: | Line 4: | ||
==Overview== | ==Overview== | ||
==Pathogenesis== | ==Pathogenesis== | ||
* Medulloblastoma arises from embryonal cells, which are stem cells that are normally involved in development of the fourth ventricle. | |||
==Genetics== | ==Genetics== | ||
* Development of medulloblastoma is the result of multiple genetic mutations. | |||
* Genes involved in the pathogenesis of medulloblastoma include: | |||
:*CTNNB1 | |||
:*PTCH1 | |||
:*MLL2 | |||
:*SMARCA4 | |||
:*DDX3X | |||
:*CTDNEP | |||
:*KDM6A | |||
:*TBR1 | |||
==Associated Conditions== | ==Associated Conditions== | ||
==Gross Pathology== | ==Gross Pathology== | ||
Revision as of 15:05, 10 November 2015
|
Medulloblastoma Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Case studies |
|
Sandbox: maria On the Web |
|
American Roentgen Ray Society Images of Sandbox: maria |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Haytham Allaham, M.D. [2]
Overview
Pathogenesis
- Medulloblastoma arises from embryonal cells, which are stem cells that are normally involved in development of the fourth ventricle.
Genetics
- Development of medulloblastoma is the result of multiple genetic mutations.
- Genes involved in the pathogenesis of medulloblastoma include:
- CTNNB1
- PTCH1
- MLL2
- SMARCA4
- DDX3X
- CTDNEP
- KDM6A
- TBR1