Intracerebral metastases pathophysiology: Difference between revisions
Jump to navigation
Jump to search
No edit summary |
|||
| Line 25: | Line 25: | ||
===Microscopic Pathology=== | ===Microscopic Pathology=== | ||
Typically well-demarcated with the exception of melanoma metastases. | Typically well-demarcated with the exception of melanoma metastases. | ||
*The histopathological appearance of intracerebral metastases may vary with the type of primary cancer. Common findings are listed below:<ref name=microscopicpathologyofintracerebralmetastasis1>Microscopic features of brain metastasis. Libre pathology 2015. http://librepathology.org/wiki/index.php/Brain_metastasis. Accessed on November 10, 2015</ref> | |||
:*Tubule formation/glands | |||
:*Usually well-circumscribed and sharply demarcated from surrounding tissue (with the exception of melanoma metastasis) | |||
:*[[Mitoses]] | |||
:*[[atypia|Nuclear atypia]] | |||
::*Nuclear hyperchromasia | |||
::*Variation of nuclear size | |||
::*Variation of nuclear shape | |||
==References== | ==References== | ||
Revision as of 15:28, 10 November 2015
|
Intracerebral metastases Microchapters |
|
Differentiating Intracerebral Metastases from other Diseases |
|---|
|
Diagnosis |
|
Treatment |
|
Case Studies |
|
Intracerebral metastases pathophysiology On the Web |
|
American Roentgen Ray Society Images of Intracerebral metastases pathophysiology |
|
Risk calculators and risk factors for Intracerebral metastases pathophysiology |
Please help WikiDoc by adding more content here. It's easy! Click here to learn about editing.
Overview
Pathophysiology
Pathogenesis
Gross Pathology
- Typically metastases are sharply demarcated from the surrounding parenchyme and usually there is a zone of peritumoral edema out of proportion with the tumor size.
- Common intracranial sites associated with subependymal giant cell astrocytoma include:[1]
- Cerebrum (80%)
- Cerebellum (15%)
- Brain stem (5% )
Gallery
-
![This solitary brain metastasis from thyroid papillary carcinoma resulted in neurological symptoms. The thyroid primary was clinically occult. (Courtesy of Dr. Nikola Kostich, Minneapolis, MN.).[2]](/images/1/12/THYROID_PAPILLARY_CARCINOMA_METASTATIC_TO_BRAIN.jpg)
This solitary brain metastasis from thyroid papillary carcinoma resulted in neurological symptoms. The thyroid primary was clinically occult. (Courtesy of Dr. Nikola Kostich, Minneapolis, MN.).[2]
![This solitary brain metastasis from thyroid papillary carcinoma resulted in neurological symptoms. The thyroid primary was clinically occult. (Courtesy of Dr. Nikola Kostich, Minneapolis, MN.).[2]](/index.php/File:THYROID_PAPILLARY_CARCINOMA_METASTATIC_TO_BRAIN.jpg)
Microscopic Pathology
Typically well-demarcated with the exception of melanoma metastases.
- The histopathological appearance of intracerebral metastases may vary with the type of primary cancer. Common findings are listed below:[3]
- Tubule formation/glands
- Usually well-circumscribed and sharply demarcated from surrounding tissue (with the exception of melanoma metastasis)
- Mitoses
- Nuclear atypia
- Nuclear hyperchromasia
- Variation of nuclear size
- Variation of nuclear shape
References
- ↑ Khuntia, Deepak (2015). "Contemporary Review of the Management of Brain Metastasis with Radiation". Advances in Neuroscience. 2015: 1–13. doi:10.1155/2015/372856. ISSN 2356-6787.
- ↑ Gross image of brain metastases. Libre pathology 2015. http://librepathology.org/wiki/index.php/Brain_metastasis. Accessed on November 10, 2015
- ↑ Microscopic features of brain metastasis. Libre pathology 2015. http://librepathology.org/wiki/index.php/Brain_metastasis. Accessed on November 10, 2015