Biliary cystadenoma and cystadenocarcinoma laboratory findings: Difference between revisions
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*Cystic fluid analysis during laparoscopy is advocated in the surgical treatment of hepatic cysts. In fact, the presence of elevated intracystic levels of CA 19-9 can support the diagnosis of cystadenoma. Therefore, it was concluded that CA 19-9 levels can differentiate between simple hepatic cyst and cystadenoma, and that cyst fluid analysis should always be performed, allowing to spare those patients with asymptomatic simple cyst from aggressive surgical treatment.<ref name="RamacciatoNigri2006">{{cite journal|last1=Ramacciato|first1=Giovanni|last2=Nigri|first2=Giuseppe R|last3=D'Angelo|first3=Francesco|last4=Aurello|first4=Paolo|last5=Bellagamba|first5=Riccardo|last6=Colarossi|first6=Cristina|last7=Pilozzi|first7=Emanuela|last8=Del Gaudio|first8=Massimo|journal=World Journal of Surgical Oncology|volume=4|issue=1|year=2006|pages=76|issn=14777819|doi=10.1186/1477-7819-4-76}}</ref> | *Cystic fluid analysis during laparoscopy is advocated in the surgical treatment of hepatic cysts. In fact, the presence of elevated intracystic levels of CA 19-9 can support the diagnosis of cystadenoma. Therefore, it was concluded that CA 19-9 levels can differentiate between simple hepatic cyst and cystadenoma, and that cyst fluid analysis should always be performed, allowing to spare those patients with asymptomatic simple cyst from aggressive surgical treatment.<ref name="RamacciatoNigri2006">{{cite journal|last1=Ramacciato|first1=Giovanni|last2=Nigri|first2=Giuseppe R|last3=D'Angelo|first3=Francesco|last4=Aurello|first4=Paolo|last5=Bellagamba|first5=Riccardo|last6=Colarossi|first6=Cristina|last7=Pilozzi|first7=Emanuela|last8=Del Gaudio|first8=Massimo|journal=World Journal of Surgical Oncology|volume=4|issue=1|year=2006|pages=76|issn=14777819|doi=10.1186/1477-7819-4-76}}</ref> | ||
*Elevated CEA and CA 19-9 in the serum or the cystic fluid aids in diagnosis and follow-up of patients. A normal level does not exclude a biliary cystadenoma; some simple liver cysts may also show elevated serum or cystic fluid CEA or CA 19-9.<ref name="Ahanatha PillaiVelayutham2012">{{cite journal|last1=Ahanatha Pillai|first1=Sastha|last2=Velayutham|first2=Vimalraj|last3=Perumal|first3=Senthilkumar|last4=Ulagendra Perumal|first4=Srinivasan|last5=Lakshmanan|first5=Anand|last6=Ramaswami|first6=Sukumar|last7=Ramasamy|first7=Ravi|last8=Sathyanesan|first8=Jeswanth|last9=Palaniappan|first9=Ravichandran|last10=Rajagopal|first10=Surendran|title=Biliary Cystadenomas: A Case for Complete Resection|journal=HPB Surgery|volume=2012|year=2012|pages=1–6|issn=0894-8569|doi=10.1155/2012/501705}}</ref> | |||
==References== | |||
==References== | ==References== | ||
Revision as of 21:41, 17 November 2015
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Laboratory Findings
- Laboratory tests may show leukocytosis with a left shift in case of superinfection of the tumor.
- Elevation of alkaline phosphatase and bilirubin may be present.
- CA 19-9 may be elevated in the serum and in the cystic fluid, while CEA and α-fetoprotein levels are usually normal.
- Cystic fluid analysis during laparoscopy is advocated in the surgical treatment of hepatic cysts. In fact, the presence of elevated intracystic levels of CA 19-9 can support the diagnosis of cystadenoma. Therefore, it was concluded that CA 19-9 levels can differentiate between simple hepatic cyst and cystadenoma, and that cyst fluid analysis should always be performed, allowing to spare those patients with asymptomatic simple cyst from aggressive surgical treatment.[1]
- Elevated CEA and CA 19-9 in the serum or the cystic fluid aids in diagnosis and follow-up of patients. A normal level does not exclude a biliary cystadenoma; some simple liver cysts may also show elevated serum or cystic fluid CEA or CA 19-9.[2]
References
References
- ↑ Ramacciato, Giovanni; Nigri, Giuseppe R; D'Angelo, Francesco; Aurello, Paolo; Bellagamba, Riccardo; Colarossi, Cristina; Pilozzi, Emanuela; Del Gaudio, Massimo (2006). World Journal of Surgical Oncology. 4 (1): 76. doi:10.1186/1477-7819-4-76. ISSN 1477-7819. Missing or empty
|title=(help) - ↑ Ahanatha Pillai, Sastha; Velayutham, Vimalraj; Perumal, Senthilkumar; Ulagendra Perumal, Srinivasan; Lakshmanan, Anand; Ramaswami, Sukumar; Ramasamy, Ravi; Sathyanesan, Jeswanth; Palaniappan, Ravichandran; Rajagopal, Surendran (2012). "Biliary Cystadenomas: A Case for Complete Resection". HPB Surgery. 2012: 1–6. doi:10.1155/2012/501705. ISSN 0894-8569.