Sandbox: Bone DDx: Difference between revisions
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* Lack of periosteal reaction | * Lack of periosteal reaction | ||
* Biphasic tumor | |||
* Fibro-osseous component includes spindle cells | |||
* Epithelial component includes nests of basaloid cells | |||
* p53 gene mutations | * p53 gene mutations | ||
Revision as of 14:20, 23 November 2015
- 20-30 yo male
- Gradual dull bone pain at the tibial area
- Leg swelling
- Islands of epithelial cells are found in a fibrous stroma
- Well-demarcated, eccentric/epicenteric, expansile, osteolytic, cortical lesion on X ray
- Located at the tibial diaphysis
- Areas of lysis interspersed with areas of sclerosis
- Lack of periosteal reaction
- Biphasic tumor
- Fibro-osseous component includes spindle cells
- Epithelial component includes nests of basaloid cells
- p53 gene mutations