Sandbox: Bone DDx: Difference between revisions

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* <20 yo males
progressive pain
* Joint pain, muscle wasting, tenderness, and swelling/local mass
bony swelling
restricted range of movement in affected limb
* Well defined lucent lesions located at the epiphysis
metaphyseal region of long bones
* Lobulated margins with a thin sclerotic rim
variable combination on chondroid, myxoid, and fibrous tissue components
* Internal calcifications
pseudolobulated architecture
* Joint effusion
 
* Abundant extracellular material
* Eosinophilic cytoplasm
* Calcifications surround cells nests
* Chickenwire appearance
 
* S100+ve
* Vimentin +ve

Revision as of 18:10, 23 November 2015

progressive pain bony swelling restricted range of movement in affected limb metaphyseal region of long bones variable combination on chondroid, myxoid, and fibrous tissue components pseudolobulated architecture