Sandbox: Bone DDx: Difference between revisions

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* Bi-nucleation.
* Bi-nucleation
* Hypochromatic enlarged nuclei.
* Hypochromatic enlarged nuclei
* Infiltration of lamellar bone ("invasion")
* Infiltration of lamellar bone ("invasion")
* Increased cellularity
* Increased cellularity

Revision as of 18:56, 23 November 2015

  • 50-70 yo males
  • Deep, achy, dull pain
  • Night time bone pain
  • Limited range of joints motion
  • Pathologic fracture
  • Palpable lump or local mass effect
  • Large calcified lesions
  • Thin and expanded bone
  • Multiple surface erosions
  • Cortical thickening


  • Lytic intralesional calcification
  • Endosteal scalloping
  • Moth eaten appearance
  • Cortical remodelling, thickening and periosteal reaction


  • Bi-nucleation
  • Hypochromatic enlarged nuclei
  • Infiltration of lamellar bone ("invasion")
  • Increased cellularity