Sandbox: Bone DDx: Difference between revisions

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* 50-70 yo males
20 yo patients
* Deep, achy,  dull pain
Abundant collagenous stroma
* Night time bone pain
Little cellularity
* Limited range of joints motion
* Pathologic fracture
 
* Palpable lump or local mass effect
 
* Large calcified lesions
* Thin and expanded bone
* Multiple surface erosions
* Cortical thickening
 
 
* Lytic intralesional calcification
* Endosteal scalloping
* Moth eaten appearance
* Cortical remodelling, thickening and periosteal reaction
 
 
* Bi-nucleation
* Hypochromatic enlarged nuclei
* Nuclear atypia
* Infiltration of lamellar bone ("invasion")
* Increased cellularity

Revision as of 19:26, 23 November 2015

20 yo patients

Abundant collagenous stroma Little cellularity