Myxoma laboratory tests: Difference between revisions
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*[[Leukocytosis]] | *[[Leukocytosis]] | ||
*Elevated [[erythrocyte sedimentation rate]](ESR) | *Elevated [[erythrocyte sedimentation rate]](ESR) | ||
*[[C-reactive protein]] | *Elevated [[C-reactive protein]] | ||
*Serum globulin level (Hypergammaglobulinemia) a1-globulin serum levels can be found in patients with cardiac myxoma, and have been proposed as predictive markers of embolic accidents. <ref name="pmid10064362">{{cite journal |vauthors=Jelic J, Milicić D, Alfirević I, Anić D, Baudoin Z, Bulat C, Corić V, Dadić D, Husar J, Ivanćan V, Korda Z, Letica D, Predrijevac M, Ugljen R, Vućemilo I |title=Cardiac myxoma: diagnostic approach, surgical treatment and follow-up. A twenty years experience |journal=J Cardiovasc Surg (Torino) |volume=37 |issue=6 Suppl 1 |pages=113–7 |year=1996 |pmid=10064362 |doi= |url=}}</ref> | *Serum globulin level (Hypergammaglobulinemia) a1-globulin serum levels can be found in patients with cardiac myxoma, and have been proposed as predictive markers of embolic accidents. <ref name="pmid10064362">{{cite journal |vauthors=Jelic J, Milicić D, Alfirević I, Anić D, Baudoin Z, Bulat C, Corić V, Dadić D, Husar J, Ivanćan V, Korda Z, Letica D, Predrijevac M, Ugljen R, Vućemilo I |title=Cardiac myxoma: diagnostic approach, surgical treatment and follow-up. A twenty years experience |journal=J Cardiovasc Surg (Torino) |volume=37 |issue=6 Suppl 1 |pages=113–7 |year=1996 |pmid=10064362 |doi= |url=}}</ref> | ||
*Serum [[IL-6]] - Atrial myxoma cells are capable of producing IL-6. Consequently, IL-6 is used as a marker of recurrence in cardiac myxomas.<ref name="pmid26351445">{{cite journal |vauthors=Ezerioha N, Feng W |title=Intracardiac Myxoma, Cerebral Aneurysms and Elevated Interleukin-6 |journal=Case Rep Neurol |volume=7 |issue=2 |pages=152–5 |year=2015 |pmid=26351445 |pmc=4560324 |doi=10.1159/000437256 |url=}}</ref> | *Serum [[IL-6]] - Atrial myxoma cells are capable of producing IL-6. Consequently, IL-6 is used as a marker of recurrence in cardiac myxomas.<ref name="pmid26351445">{{cite journal |vauthors=Ezerioha N, Feng W |title=Intracardiac Myxoma, Cerebral Aneurysms and Elevated Interleukin-6 |journal=Case Rep Neurol |volume=7 |issue=2 |pages=152–5 |year=2015 |pmid=26351445 |pmc=4560324 |doi=10.1159/000437256 |url=}}</ref> | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Ahmad Al Maradni, M.D. [2]Maria Fernanda Villarreal, M.D. [3]
Overview
Laboratory findings consistent with cardiac myxoma include anemia, leukocytosis and elevated erythrocyte sedimentation rate. However, these results are generally non-diagnostic.
Laboratory Findings
The clinical utility of laboratory tests in the diagnosis of cardiac myxoma remains nonspecific.[1]
Blood tests
There is no specific blood test for the diagnosis of cardiac myxoma. However, constitutional symptoms are associated with the following blood count (CBC) findings:[2]
- Anemia - Normochromic or hypochromic.
- Leukocytosis
- Elevated erythrocyte sedimentation rate(ESR)
- Elevated C-reactive protein
- Serum globulin level (Hypergammaglobulinemia) a1-globulin serum levels can be found in patients with cardiac myxoma, and have been proposed as predictive markers of embolic accidents. [3]
- Serum IL-6 - Atrial myxoma cells are capable of producing IL-6. Consequently, IL-6 is used as a marker of recurrence in cardiac myxomas.[4]
References
- ↑ Reynen K (1995). "Cardiac myxomas". N. Engl. J. Med. 333 (24): 1610–7. doi:10.1056/NEJM199512143332407. PMID 7477198.
- ↑ Hartig I, Kraatz EG, Beurich HW, Moosig F (2014). "[Atrial myxoma with clinical signs of systemic inflammatory disease.]". Z Rheumatol. doi:10.1007/s00393-013-1347-y. PMID 24599357.
- ↑ Jelic J, Milicić D, Alfirević I, Anić D, Baudoin Z, Bulat C, Corić V, Dadić D, Husar J, Ivanćan V, Korda Z, Letica D, Predrijevac M, Ugljen R, Vućemilo I (1996). "Cardiac myxoma: diagnostic approach, surgical treatment and follow-up. A twenty years experience". J Cardiovasc Surg (Torino). 37 (6 Suppl 1): 113–7. PMID 10064362.
- ↑ Ezerioha N, Feng W (2015). "Intracardiac Myxoma, Cerebral Aneurysms and Elevated Interleukin-6". Case Rep Neurol. 7 (2): 152–5. doi:10.1159/000437256. PMC 4560324. PMID 26351445.