Pineal teratoma: Difference between revisions
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*Pineal teratoma is an uncommon extra-axial intracranial cancer, which can have a bewildering variety of components and thus a wide range of appearances.<ref name=overviewpt1>Intracranial teratomas. Dr Alexandra Stanislavsky and Frank Gaillard et al. Radiopaedia 2015. http://radiopaedia.org/articles/intracranial-teratoma. Accessed on December 10, 2015</ref> | *Pineal teratoma is an uncommon extra-axial intracranial cancer, which can have a bewildering variety of components and thus a wide range of appearances.<ref name=overviewpt1>Intracranial teratomas. Dr Alexandra Stanislavsky and Frank Gaillard et al. Radiopaedia 2015. http://radiopaedia.org/articles/intracranial-teratoma. Accessed on December 10, 2015</ref> | ||
*Pineal teratoma may be classified into three subtypes: mature, immature, and mature with malignant transformation. | *Pineal teratoma may be classified into three subtypes: mature, immature, and mature with malignant transformation. | ||
*Mature teratomas are benign, mature, well-differentiated cystic lesions; whereas immature teratomas are poorly differentiated lesions with solid components and malignant transformation.<ref name=overviewteratoma1>Teratoma. Dr Jeremy Jones and Frank Gaillard et al. Radiopaedia 2015. http://radiopaedia.org/articles/teratoma. Accessed on December 10, 2015</ref> | :*Mature teratomas are benign, mature, well-differentiated cystic lesions; whereas immature teratomas are poorly differentiated lesions with solid components and malignant transformation.<ref name=overviewteratoma1>Teratoma. Dr Jeremy Jones and Frank Gaillard et al. Radiopaedia 2015. http://radiopaedia.org/articles/teratoma. Accessed on December 10, 2015</ref> | ||
:*On other occasions, mature teratomas contain elements that undergo malignant transformation (most commonly squamous components). | |||
*On microscopic histopathological analysis, pineal teratoma is characterized by cells originating from at least two and usually all three embryonic layers ([[ectoderm]], [[mesoderm]], and [[endoderm]]). The histological subtype may not necessarily determine the biological behavior.<ref name=pathpt1>Pathology of extra-axial intracranial teratoma. Dr Alexandra Stanislavsky and Frank Gaillard et al. Radiopaedia 2015. http://radiopaedia.org/articles/intracranial-teratoma. Accessed on December 10, 2015</ref> | *On microscopic histopathological analysis, pineal teratoma is characterized by cells originating from at least two and usually all three embryonic layers ([[ectoderm]], [[mesoderm]], and [[endoderm]]). The histological subtype may not necessarily determine the biological behavior.<ref name=pathpt1>Pathology of extra-axial intracranial teratoma. Dr Alexandra Stanislavsky and Frank Gaillard et al. Radiopaedia 2015. http://radiopaedia.org/articles/intracranial-teratoma. Accessed on December 10, 2015</ref> | ||
*Pineal teratomas may be associated with elevated levels of [[AFP|serum alpha fetoprotein (AFP)]] or [[CEA|serum carcinoembryonic antigen (CEA)]].<ref name=pathpt1>Pathology of extra-axial intracranial teratoma. Dr Alexandra Stanislavsky and Frank Gaillard et al. Radiopaedia 2015. http://radiopaedia.org/articles/intracranial-teratoma. Accessed on December 10, 2015</ref> | *Pineal teratomas may be associated with elevated levels of [[AFP|serum alpha fetoprotein (AFP)]] or [[CEA|serum carcinoembryonic antigen (CEA)]].<ref name=pathpt1>Pathology of extra-axial intracranial teratoma. Dr Alexandra Stanislavsky and Frank Gaillard et al. Radiopaedia 2015. http://radiopaedia.org/articles/intracranial-teratoma. Accessed on December 10, 2015</ref> | ||
Revision as of 16:20, 10 December 2015
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2]
Synonyms and keywords: Pineal teratomas; Pineal teratoblastoma; Pineal teratoid tumor; Pineal germ cell tumors; Pineal gland tumors; Brain tumor
Overview
- Pineal teratoma is an uncommon extra-axial intracranial cancer, which can have a bewildering variety of components and thus a wide range of appearances.[1]
- Pineal teratoma may be classified into three subtypes: mature, immature, and mature with malignant transformation.
- Mature teratomas are benign, mature, well-differentiated cystic lesions; whereas immature teratomas are poorly differentiated lesions with solid components and malignant transformation.[2]
- On other occasions, mature teratomas contain elements that undergo malignant transformation (most commonly squamous components).
- On microscopic histopathological analysis, pineal teratoma is characterized by cells originating from at least two and usually all three embryonic layers (ectoderm, mesoderm, and endoderm). The histological subtype may not necessarily determine the biological behavior.[3]
- Pineal teratomas may be associated with elevated levels of serum alpha fetoprotein (AFP) or serum carcinoembryonic antigen (CEA).[3]
References
- ↑ Intracranial teratomas. Dr Alexandra Stanislavsky and Frank Gaillard et al. Radiopaedia 2015. http://radiopaedia.org/articles/intracranial-teratoma. Accessed on December 10, 2015
- ↑ Teratoma. Dr Jeremy Jones and Frank Gaillard et al. Radiopaedia 2015. http://radiopaedia.org/articles/teratoma. Accessed on December 10, 2015
- ↑ 3.0 3.1 Pathology of extra-axial intracranial teratoma. Dr Alexandra Stanislavsky and Frank Gaillard et al. Radiopaedia 2015. http://radiopaedia.org/articles/intracranial-teratoma. Accessed on December 10, 2015