Linitis plastica screening: Difference between revisions
Jump to navigation
Jump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
__NOTOC__ | |||
{{Linitis plastica}} | {{Linitis plastica}} | ||
{{CMG}} | {{CMG}}{{AE}} {{STM}} | ||
==Overview== | ==Overview== | ||
Patients who have a relative with hereditary diffuse gastric adenocarcinoma (HDGC) should be screened earlier for CDH1 gene mutations.<ref name=me>Hereditary diffuse gastric cancer. Genetics Home Reference. http://ghr.nlm.nih.gov/condition/hereditary-diffuse-gastric-cancer#definition Accessed on December 10, 2015</ref> | |||
==Screening== | |||
*Patients who have a relative with hereditary diffuse gastric adenocarcinoma (HDGC) should be screened earlier for CDH1 gene mutations.<ref name=me>Hereditary diffuse gastric cancer. Genetics Home Reference. http://ghr.nlm.nih.gov/condition/hereditary-diffuse-gastric-cancer#definition Accessed on December 10, 2015</ref> | |||
*Indication for prophylactic gastrectomy include CDH1 positive patients.<ref name="pmid20719348">{{cite journal| author=Pandalai PK, Lauwers GY, Chung DC, Patel D, Yoon SS| title=Prophylactic total gastrectomy for individuals with germline CDH1 mutation. | journal=Surgery | year= 2011 | volume= 149 | issue= 3 | pages= 347-55 | pmid=20719348 | doi=10.1016/j.surg.2010.07.005 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20719348 }} </ref> | |||
**The disease penetrance for the hereditary form is 80%, resulting in a very high risk of developing the cancer. | |||
==References== | ==References== | ||
Revision as of 16:34, 10 December 2015
|
Linitis plastica Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Case Studies |
|
Linitis plastica screening On the Web |
|
American Roentgen Ray Society Images of Linitis plastica screening |
|
Risk calculators and risk factors for Linitis plastica screening |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Soujanya Thummathati, MBBS [2]
Overview
Patients who have a relative with hereditary diffuse gastric adenocarcinoma (HDGC) should be screened earlier for CDH1 gene mutations.[1]
Screening
- Patients who have a relative with hereditary diffuse gastric adenocarcinoma (HDGC) should be screened earlier for CDH1 gene mutations.[1]
- Indication for prophylactic gastrectomy include CDH1 positive patients.[2]
- The disease penetrance for the hereditary form is 80%, resulting in a very high risk of developing the cancer.
References
- ↑ 1.0 1.1 Hereditary diffuse gastric cancer. Genetics Home Reference. http://ghr.nlm.nih.gov/condition/hereditary-diffuse-gastric-cancer#definition Accessed on December 10, 2015
- ↑ Pandalai PK, Lauwers GY, Chung DC, Patel D, Yoon SS (2011). "Prophylactic total gastrectomy for individuals with germline CDH1 mutation". Surgery. 149 (3): 347–55. doi:10.1016/j.surg.2010.07.005. PMID 20719348.