Neurofibroma surgery: Difference between revisions
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{{CMG}}; {{AE}} {{SC}} | {{CMG}}; {{AE}} {{SC}} | ||
==Overview== | ==Overview== | ||
[[Surgery]] is the mainstay of treatment for neurofibroma. | [[Surgery]] is the mainstay of treatment for neurofibroma.<ref name=radio> Neurofibroma. Dr Bruno Di Muzio and Dr Maxime St-Amant et al. Radiopaedia.org 2015. http://radiopaedia.org/articles/neurofibroma Accessed on November 17, 2015 </ref> | ||
==Surgery== | ==Surgery== | ||
'''Localised neurofibroma | '''Localised neurofibroma and Diffuse neurofibroma'''<ref name=radio> Neurofibroma. Dr Bruno Di Muzio and Dr Maxime St-Amant et al. Radiopaedia.org 2015. http://radiopaedia.org/articles/neurofibroma Accessed on November 17, 2015 </ref> | ||
* Localised and diffuse lesions usually be treated surgically. | * Localised and diffuse lesions usually be treated surgically. | ||
* Neurofibromas that infiltrate between [[nerve]] fascicles are unable to be separated from the parent nerve, therefore, deep-seated lesions are often managed conservatively. | * Neurofibromas that infiltrate between [[nerve]] fascicles are unable to be separated from the parent nerve, therefore, deep-seated lesions are often managed conservatively. | ||
* Local recurrence after excision is uncommon and [[malignant transformation]] is rare. | * Local recurrence after excision is uncommon and [[malignant transformation]] is rare. | ||
'''Plexiform neurofibroma'''<ref name=radio> Neurofibroma. Dr Bruno Di Muzio and Dr Maxime St-Amant et al. Radiopaedia.org 2015. http://radiopaedia.org/articles/neurofibroma </ref> | '''Plexiform neurofibroma'''<ref name=radio> Neurofibroma. Dr Bruno Di Muzio and Dr Maxime St-Amant et al. Radiopaedia.org 2015. http://radiopaedia.org/articles/neurofibroma Accessed on November 17, 2015 </ref> | ||
* The primary treatment option for [[plexiform neurofibroma]] is [[surgery]].<ref>{{cite journal |vauthors=Packer RJ, Gutmann DH, Rubenstein A, etal |title=Plexiform neurofibromas in NF1: toward biologic-based therapy |journal=Neurology |volume=58 |issue=10 |pages=1461–70 |date=May 2002 |pmid=12041525 |url=http://www.neurology.org/cgi/pmidlookup?view=long&pmid=12041525 |doi=10.1212/wnl.58.10.1461}}</ref> | * The primary treatment option for [[plexiform neurofibroma]] is [[surgery]].<ref>{{cite journal |vauthors=Packer RJ, Gutmann DH, Rubenstein A, etal |title=Plexiform neurofibromas in NF1: toward biologic-based therapy |journal=Neurology |volume=58 |issue=10 |pages=1461–70 |date=May 2002 |pmid=12041525 |url=http://www.neurology.org/cgi/pmidlookup?view=long&pmid=12041525 |doi=10.1212/wnl.58.10.1461}}</ref> | ||
* Removal of [[plexiform neurofibroma]]s is difficult because they can be large and cross [[tissue]] boundaries. | * Removal of [[plexiform neurofibroma]]s is difficult because they can be large and cross [[tissue]] boundaries. | ||
Revision as of 14:53, 18 December 2015
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Shanshan Cen, M.D. [2]
Overview
Surgery is the mainstay of treatment for neurofibroma.[1]
Surgery
Localised neurofibroma and Diffuse neurofibroma[1]
- Localised and diffuse lesions usually be treated surgically.
- Neurofibromas that infiltrate between nerve fascicles are unable to be separated from the parent nerve, therefore, deep-seated lesions are often managed conservatively.
- Local recurrence after excision is uncommon and malignant transformation is rare.
Plexiform neurofibroma[1]
- The primary treatment option for plexiform neurofibroma is surgery.[2]
- Removal of plexiform neurofibromas is difficult because they can be large and cross tissue boundaries.
- Plexiform neurofibromas are particularly difficult to resect, often leading to incomplete resection.
- Recurrence after resection is frequent.
References
- ↑ 1.0 1.1 1.2 Neurofibroma. Dr Bruno Di Muzio and Dr Maxime St-Amant et al. Radiopaedia.org 2015. http://radiopaedia.org/articles/neurofibroma Accessed on November 17, 2015
- ↑ Packer RJ, Gutmann DH, Rubenstein A, et al. (May 2002). "Plexiform neurofibromas in NF1: toward biologic-based therapy". Neurology. 58 (10): 1461–70. doi:10.1212/wnl.58.10.1461. PMID 12041525.