Biliary cystadenoma and cystadenocarcinoma laboratory findings: Difference between revisions
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==Overview== | ==Overview== | ||
==Laboratory Findings== | ==Laboratory Findings== | ||
*Laboratory tests may show leukocytosis with a left shift in case of superinfection of the tumor.<ref name="RamacciatoNigri2006">{{cite journal|last1=Ramacciato|first1=Giovanni|last2=Nigri|first2=Giuseppe R|last3=D'Angelo|first3=Francesco|last4=Aurello|first4=Paolo|last5=Bellagamba|first5=Riccardo|last6=Colarossi|first6=Cristina|last7=Pilozzi|first7=Emanuela|last8=Del Gaudio|first8=Massimo|journal=World Journal of Surgical Oncology|volume=4|issue=1|year=2006|pages=76|issn=14777819|doi=10.1186/1477-7819-4-76}}</ref> | *Laboratory tests may show [[leukocytosis]] with a left shift in case of superinfection of the tumor.<ref name="RamacciatoNigri2006">{{cite journal|last1=Ramacciato|first1=Giovanni|last2=Nigri|first2=Giuseppe R|last3=D'Angelo|first3=Francesco|last4=Aurello|first4=Paolo|last5=Bellagamba|first5=Riccardo|last6=Colarossi|first6=Cristina|last7=Pilozzi|first7=Emanuela|last8=Del Gaudio|first8=Massimo|journal=World Journal of Surgical Oncology|volume=4|issue=1|year=2006|pages=76|issn=14777819|doi=10.1186/1477-7819-4-76}}</ref> | ||
*Elevation of alkaline phosphatase and bilirubin may be present. | *Elevation of [[alkaline phosphatase]] and [[bilirubin]] may be present. | ||
*CA 19-9 may be elevated in the serum and in the cystic fluid, while CEA and α-fetoprotein levels are usually normal. | *[[CA 19-9]] may be elevated in the serum and in the cystic fluid, while CEA and α-fetoprotein levels are usually normal. | ||
===Cystic fluid analysis=== | ===Cystic fluid analysis=== | ||
Cystic fluid analysis during laparoscopy is advocated in the surgical treatment of hepatic cysts. In fact, the presence of elevated intracystic levels of CA 19-9 can support the diagnosis of cystadenoma. Therefore, it was concluded that CA 19-9 levels can differentiate between simple hepatic cyst and cystadenoma, and that cyst fluid analysis should always be performed, allowing to spare those patients with asymptomatic simple cyst from aggressive surgical treatment.<ref name="RamacciatoNigri2006">{{cite journal|last1=Ramacciato|first1=Giovanni|last2=Nigri|first2=Giuseppe R|last3=D'Angelo|first3=Francesco|last4=Aurello|first4=Paolo|last5=Bellagamba|first5=Riccardo|last6=Colarossi|first6=Cristina|last7=Pilozzi|first7=Emanuela|last8=Del Gaudio|first8=Massimo|journal=World Journal of Surgical Oncology|volume=4|issue=1|year=2006|pages=76|issn=14777819|doi=10.1186/1477-7819-4-76}}</ref> | Cystic fluid analysis during [[laparoscopy]] is advocated in the surgical treatment of hepatic cysts. In fact, the presence of elevated intracystic levels of CA 19-9 can support the diagnosis of cystadenoma. Therefore, it was concluded that [[CA 19-9]] levels can differentiate between simple hepatic cyst and cystadenoma, and that cyst fluid analysis should always be performed, allowing to spare those patients with asymptomatic simple cyst from aggressive surgical treatment.<ref name="RamacciatoNigri2006">{{cite journal|last1=Ramacciato|first1=Giovanni|last2=Nigri|first2=Giuseppe R|last3=D'Angelo|first3=Francesco|last4=Aurello|first4=Paolo|last5=Bellagamba|first5=Riccardo|last6=Colarossi|first6=Cristina|last7=Pilozzi|first7=Emanuela|last8=Del Gaudio|first8=Massimo|journal=World Journal of Surgical Oncology|volume=4|issue=1|year=2006|pages=76|issn=14777819|doi=10.1186/1477-7819-4-76}}</ref> | ||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
Revision as of 20:00, 18 December 2015
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Biliary cystadenoma and cystadenocarcinoma Microchapters |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Suveenkrishna Pothuru, M.B,B.S. [2]
Overview
Laboratory Findings
- Laboratory tests may show leukocytosis with a left shift in case of superinfection of the tumor.[1]
- Elevation of alkaline phosphatase and bilirubin may be present.
- CA 19-9 may be elevated in the serum and in the cystic fluid, while CEA and α-fetoprotein levels are usually normal.
Cystic fluid analysis
Cystic fluid analysis during laparoscopy is advocated in the surgical treatment of hepatic cysts. In fact, the presence of elevated intracystic levels of CA 19-9 can support the diagnosis of cystadenoma. Therefore, it was concluded that CA 19-9 levels can differentiate between simple hepatic cyst and cystadenoma, and that cyst fluid analysis should always be performed, allowing to spare those patients with asymptomatic simple cyst from aggressive surgical treatment.[1]
References
- ↑ 1.0 1.1 Ramacciato, Giovanni; Nigri, Giuseppe R; D'Angelo, Francesco; Aurello, Paolo; Bellagamba, Riccardo; Colarossi, Cristina; Pilozzi, Emanuela; Del Gaudio, Massimo (2006). World Journal of Surgical Oncology. 4 (1): 76. doi:10.1186/1477-7819-4-76. ISSN 1477-7819. Missing or empty
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