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==Staging of Sacrococcygeal Teratoma==
According to Gonzalez-Crussi System, Sacrococcygeal teratoma is graded on a scale from 0-3, based on the histology:<ref name = "cs">Myers LB, Bulich LA. Anesthesia for Fetal Intervention and Surgery. PMPH-USA; 2005.</ref><ref name = "ad">{{cite journal |vauthors=Harms D, Zahn S, Göbel U, Schneider DT |title=Pathology and molecular biology of teratomas in childhood and adolescence |journal=Klin Padiatr |volume=218 |issue=6 |pages=296–302 |year=2006 |pmid=17080330 |doi=10.1055/s-2006-942271 |url=}}</ref>


{| style="border: 0px; font-size: 90%; margin: 3px; width: 800px"
{| style="border: 0px; font-size: 90%; margin: 3px; width: 800px"
|valign=top|
|valign=top|
|+
|+
! style="background: #4479BA; width: 100px;" | {{fontcolor|#FFF|Stage  }}
! style="background: #4479BA; width: 100px;" | {{fontcolor|#FFF|Grade}}
! style="background: #4479BA; width: 400px;" | {{fontcolor|#FFF|Features}}
! style="background: #4479BA; width: 400px;" | {{fontcolor|#FFF|Microscopic Features}}
|-
|-
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" |
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" |
'''Stage I'''
'''Grade 0'''
| style="padding: 5px 5px; background: #F5F5F5;" |
| style="padding: 5px 5px; background: #F5F5F5;" |
*Complete resection; negative tumor margins
*Tumor contains only mature tissue
|-
|-
| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |
| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |
'''Stage II'''
'''Grade I'''
| style="padding: 5px 5px; background: #F5F5F5;" |
| style="padding: 5px 5px; background: #F5F5F5;" |
*Microscopic residuals; lymph node negative
*Tumor contains rare foci of immature tissues
*Less than 10% tissue is Immature
|-
|-
| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |
| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |
'''Stage III'''
'''Grade II'''
| style="padding: 5px 5px; background: #F5F5F5;" |
| style="padding: 5px 5px; background: #F5F5F5;" |
*Lymph node involvement; Gross residual on biopsy; retroperitoneal node may be positive or negative
* Tumor contains moderate quantities of immature tissues.
* Upto 10-50% tissue in immature
|-
|-
| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |
| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |
'''Stage IV'''
'''Grade III'''
| style="padding: 5px 5px; background: #F5F5F5;" |
*Tumor contains large quantities of immature tissue with or without malignant yolk sac elements.
*More than 50% tissue is immature
|}

Revision as of 16:03, 21 December 2015

According to Gonzalez-Crussi System, Sacrococcygeal teratoma is graded on a scale from 0-3, based on the histology:[1][2]

Grade Microscopic Features

Grade 0

  • Tumor contains only mature tissue

Grade I

  • Tumor contains rare foci of immature tissues
  • Less than 10% tissue is Immature

Grade II

  • Tumor contains moderate quantities of immature tissues.
  • Upto 10-50% tissue in immature

Grade III

  • Tumor contains large quantities of immature tissue with or without malignant yolk sac elements.
  • More than 50% tissue is immature
  1. ↑ Myers LB, Bulich LA. Anesthesia for Fetal Intervention and Surgery. PMPH-USA; 2005.
  2. ↑ Harms D, Zahn S, Göbel U, Schneider DT (2006). "Pathology and molecular biology of teratomas in childhood and adolescence". Klin Padiatr. 218 (6): 296–302. doi:10.1055/s-2006-942271. PMID 17080330.
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