Chondroma natural history

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Soujanya Thummathati, MBBS [2]

Overview

If left untreated, patients with chondroma may progress to develop pain and discomfort. Common complications of chondroma include malignant transformation into a low grade chondrosarcoma, pathologic fractures and skeletal deformities

Natural History

If left untreated, patients with chondroma may progress to develop pain and discomfort. If an enchondroma is painful in the absence of a fracture, it should be considered malignant, unless proven otherwise.

Complications

Common complications of chondroma include:

• Malignant transformation into a low grade chondrosarcoma
  • Sarcomatous changes in solitary enchondromas is rare. Risk is higher in Ollier's disease and Maffucci syndrome.
• Pathologic fractures
• Skeletal deformities

Prognosis

Prognosis is generally good for solitary chondromas and after surgical excision of

References

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