Rocky Mountain spotted fever pathophysiology: Difference between revisions
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Created page with "{{Rocky Mountain spotted fever}} {{CMG}} ==Overview== == Pathophysiology & Etiology== [[Image:Cells.jpg|left|thumb|180px|Gimenez stain of tick hemolymph cells infected with ..." |
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== Pathophysiology & Etiology== | == Pathophysiology & Etiology== | ||
[[Image:Cells.jpg|left|thumb|180px|Gimenez stain of tick hemolymph cells infected with R. rickettsii]] | [[Image:Cells.jpg|left|thumb|180px|Gimenez stain of tick hemolymph cells infected with R. rickettsii]] | ||
Rocky Mountain spotted fever is caused by Rickettsia rickettsii, a small bacterium that grows inside the cells of its hosts. These bacteria range in size from 0.2 x 0.5 micrometers to 0.3 x 2.0 micrometers. They are difficult to see in tissues by using routine histologic stains and generally require the use of special staining methods. | *Rocky Mountain spotted fever is caused by Rickettsia rickettsii, a small bacterium that grows inside the cells of its hosts. | ||
*These bacteria range in size from 0.2 x 0.5 micrometers to 0.3 x 2.0 micrometers. | |||
*They are difficult to see in tissues by using routine histologic stains and generally require the use of special staining methods. | |||
In the human body, rickettsiae live and multiply primarily within cells that line small- to medium-sized blood vessels. Spotted fever group rickettsiae can grow in the cytoplasm or in the nucleus of the host cell. Once inside the host the rickettsiae multiply, resulting in damage and death to these cells. This causes blood to leak through tiny holes in vessel walls into adjacent tissues. | *In the human body, rickettsiae live and multiply primarily within cells that line small- to medium-sized blood vessels. | ||
*Spotted fever group rickettsiae can grow in the cytoplasm or in the nucleus of the host cell. | |||
*Once inside the host the rickettsiae multiply, resulting in damage and death to these cells. | |||
*This causes blood to leak through tiny holes in vessel walls into adjacent tissues. | |||
*In turn the leakage process causes the rash that is traditionally associated with Rocky Mountain spotted fever and also causes damage to organs and tissues. | |||
===Taxonomy=== | |||
{| style="border: 0px; font-size: 100%; margin: 3px; width: 800px" align=center | |||
! style="background: #4479BA; text-align:left; padding: 5px 5px;" colspan="2"| {{fontcolor|#FFF|Classifications}} | |||
|- | |||
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" | Domain | |||
| style="padding: 5px 5px; background: #F5F5F5;" | Bacteria | |||
|- | |||
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" | Kingdom | |||
| style="padding: 5px 5px; background: #F5F5F5;" | Prokaryote | |||
|- | |||
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" | Phylum | |||
| style="padding: 5px 5px; background: #F5F5F5;" | Proteobacteria | |||
|- | |||
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" | Class | |||
| style="padding: 5px 5px; background: #F5F5F5;" | Alpha Protobacteria | |||
|- | |||
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" | Order | |||
| style="padding: 5px 5px; background: #F5F5F5;" | Rickettsiales | |||
|- | |||
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" | Family | |||
| style="padding: 5px 5px; background: #F5F5F5;" | Rickettsiaceae | |||
|- | |||
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" | Genus | |||
| style="padding: 5px 5px; background: #F5F5F5;" | Rickettsia | |||
|- | |||
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" | Species | |||
| style="padding: 5px 5px; background: #F5F5F5;" | Rickettsii | |||
|} | |||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
Revision as of 19:16, 31 December 2015
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Rocky Mountain spotted fever Microchapters |
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Differentiating Rocky Mountain spotted fever from other Diseases |
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Diagnosis |
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Treatment |
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Case Studies |
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Rocky Mountain spotted fever pathophysiology On the Web |
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American Roentgen Ray Society Images of Rocky Mountain spotted fever pathophysiology |
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Directions to Hospitals Treating Rocky Mountain spotted fever |
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Risk calculators and risk factors for Rocky Mountain spotted fever pathophysiology |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Pathophysiology & Etiology
- Rocky Mountain spotted fever is caused by Rickettsia rickettsii, a small bacterium that grows inside the cells of its hosts.
- These bacteria range in size from 0.2 x 0.5 micrometers to 0.3 x 2.0 micrometers.
- They are difficult to see in tissues by using routine histologic stains and generally require the use of special staining methods.
- In the human body, rickettsiae live and multiply primarily within cells that line small- to medium-sized blood vessels.
- Spotted fever group rickettsiae can grow in the cytoplasm or in the nucleus of the host cell.
- Once inside the host the rickettsiae multiply, resulting in damage and death to these cells.
- This causes blood to leak through tiny holes in vessel walls into adjacent tissues.
- In turn the leakage process causes the rash that is traditionally associated with Rocky Mountain spotted fever and also causes damage to organs and tissues.
Taxonomy
| Classifications | |
|---|---|
| Domain | Bacteria |
| Kingdom | Prokaryote |
| Phylum | Proteobacteria |
| Class | Alpha Protobacteria |
| Order | Rickettsiales |
| Family | Rickettsiaceae |
| Genus | Rickettsia |
| Species | Rickettsii |