Pertussis other diagnostic studies: Difference between revisions
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==Other Diagnostic Studies== | ==Other Diagnostic Studies== | ||
* [[Polymerase chain reaction]] (PCR) | * [[Polymerase chain reaction]] (PCR) | ||
** PCR has excellent sensitivity and can be performed rapidly. <ref name = CDCPertussis>{{cite web |url=http://www.cdc.gov/pertussis/clinical/diagnostic-testing/diagnosis-confirmation.html |title=Pertussis | Whooping Cough | Diagnosis Confirmation | CDC |format= |work= |accessdate=}}</ref> | ** PCR has excellent sensitivity and can be performed rapidly.<ref name = CDCPertussis>{{cite web |url=http://www.cdc.gov/pertussis/clinical/diagnostic-testing/diagnosis-confirmation.html |title=Pertussis | Whooping Cough | Diagnosis Confirmation | CDC |format= |work= |accessdate=}}</ref> | ||
** PCR | ** PCR is most accurately performed within 4 weeks of cough onset; performed post 4-weeks greatly raises the chance of false-negative readings.<ref name = CDCPertussis>{{cite web |url=http://www.cdc.gov/pertussis/clinical/diagnostic-testing/diagnosis-confirmation.html |title=Pertussis | Whooping Cough | Diagnosis Confirmation | CDC |format= |work= |accessdate=}}</ref> | ||
* [[Direct fluorescent antibody]] (DFA) testing | * [[Direct fluorescent antibody]] (DFA) testing | ||
** | ** DFA's positives include inexpensive cost and rapid results.<ref name = PMC85400>{{cite journal |vauthors=Miagkaia IP |title=[Antireticular cytotoxic serum as an agent for stimulating the immunity system] |language=Russian |journal=Zh. Mikrobiol. Epidemiol. Immunobiol. |volume= |issue=12 |pages=82–6 |year=1978 |pmid=85400 |doi= |url=}}</ref> | ||
** | ** DFA's drawbacks include poor sensitivity and specificity. | ||
* Pulsed-field gel electrophoresis (PFGE) | * Pulsed-field gel electrophoresis (PFGE) | ||
** It is a [[DNA fingerprinting]] technique that may be useful for epidemiological purposes | ** It is a [[DNA fingerprinting]] technique that may be useful for epidemiological purposes. | ||
==References== | ==References== | ||
Revision as of 14:47, 7 January 2016
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aditya Govindavarjhulla, M.B.B.S. [2]
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Other Diagnostic Studies
- Polymerase chain reaction (PCR)
- Direct fluorescent antibody (DFA) testing
- DFA's positives include inexpensive cost and rapid results.[2]
- DFA's drawbacks include poor sensitivity and specificity.
- Pulsed-field gel electrophoresis (PFGE)
- It is a DNA fingerprinting technique that may be useful for epidemiological purposes.