Sporotrichosis pathophysiology

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Alison Leibowitz [2]

Pathophysiology

Transmission

• S. schenckii is usually transmitted to the human host via posttraumatic inoculation. However, sporotrichosis may also develop as a result of spore inhalation, although this mode of transmission is infrequent.
• Modes of transmission either lead to direct inoculation or enable the entry of the fungus.

• Actions, such as handling thorny plants, sphagnum moss, bales of hay, or any plant or plant product that can cause skin trauma, may enable S. schenckii entry.

Pathogenesis

The pathophysiology of sporotrichosis depends on the histological subtype.