Sporotrichosis medical therapy: Difference between revisions
Jump to navigation
Jump to search
Line 13: | Line 13: | ||
|Uncomplicated cutaneous | |Uncomplicated cutaneous | ||
|Itraconazole [200 mg/day] | |Itraconazole [200 mg/day] | ||
|Itraconazole [200 b.i.d.], | |Itraconazole [200 b.i.d.], terbinafine [500 b.i.d.], SSKI [increasing doses], fluconazole [400-800 mg/day], or local hyperthermia | ||
terbinafine [500 b.i.d.], | |||
SSKI [increasing doses], | |||
fluconazole [400-800 mg/day], or | |||
local hyperthermia | |||
|Continue treatment for 2-4 weeks after lesions resolve. | |Continue treatment for 2-4 weeks after lesions resolve. | ||
|- | |- | ||
Line 31: | Line 23: | ||
|Pulmonary | |Pulmonary | ||
|Limposomal amphotericin B [3-5 mg/kg/day], followed by itraconazole [200 mg b.i.d.] | |Limposomal amphotericin B [3-5 mg/kg/day], followed by itraconazole [200 mg b.i.d.] | ||
|Deoxycholate amphotericin B [0.7-1 mg/kg/day], followed by itraconazole upon symptom resolution | |Deoxycholate amphotericin B [0.7-1 mg/kg/day], followed by itraconazole [200 mg b.i.d.] upon symptom resolution | ||
|Treat less sever cases with a 12 month regimen of itraconazole. | |Treat less sever cases with a 12 month regimen of itraconazole. | ||
|- | |- | ||
|Meningeal | |Meningeal | ||
|Limposomal amphotericin B [3-5 mg/kg/day], followed by itraconazole [200 mg b.i.d.] | |Limposomal amphotericin B [3-5 mg/kg/day], followed by itraconazole [200 mg b.i.d.] | ||
|Deoxycholate amphotericin B [0.7-1 mg/kg/day], followed by itraconazole upon symptom resolution | |Deoxycholate amphotericin B [0.7-1 mg/kg/day], followed by itraconazole [200 mg b.i.d.] upon symptom resolution | ||
|Precise length of amphotericin B treatment varies. Suppressive treatment with itraconazole is necessary. | |Precise length of amphotericin B treatment varies. Suppressive treatment with itraconazole is necessary. | ||
|- | |- | ||
|Dissimated | |Dissimated | ||
| | |Limposomal amphotericin B [3-5 mg/kg/day], followed by itraconazole [200 mg b.i.d.] | ||
| | |Deoxycholate amphotericin B [0.7-1 mg/kg/day], followed by itraconazole [200 mg b.i.d.] upon symptom resolution | ||
| | |Continue amphotericin B treatment until patient shows marked improvement for a minimum of 12 months. Suppressive treatment with itraconazole is necessary. | ||
|- | |- | ||
|Sporotrichosis in pregnant women | |Sporotrichosis in pregnant women |
Revision as of 15:47, 12 January 2016
Sporotrichosis Microchapters |
Diagnosis |
---|
Treatment |
Case Studies |
Sporotrichosis medical therapy On the Web |
American Roentgen Ray Society Images of Sporotrichosis medical therapy |
Risk calculators and risk factors for Sporotrichosis medical therapy |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Alison Leibowitz [2]
Treatment
Form | Primary Line of Treatment | Alternative Treatment | Remarks/Other |
---|---|---|---|
Uncomplicated cutaneous | Itraconazole [200 mg/day] | Itraconazole [200 b.i.d.], terbinafine [500 b.i.d.], SSKI [increasing doses], fluconazole [400-800 mg/day], or local hyperthermia | Continue treatment for 2-4 weeks after lesions resolve. |
Osteoarticular | Itraconazole [200 mg b.i.d.] | Limposomal amphotericin B [3-5 mg/kg/day] or deoxycholate amphotericin B [0.7-1 mg/kg/day] until symptom resolution | For a total of 12 months, switch to itraconazole after resolution/end of treatment. |
Pulmonary | Limposomal amphotericin B [3-5 mg/kg/day], followed by itraconazole [200 mg b.i.d.] | Deoxycholate amphotericin B [0.7-1 mg/kg/day], followed by itraconazole [200 mg b.i.d.] upon symptom resolution | Treat less sever cases with a 12 month regimen of itraconazole. |
Meningeal | Limposomal amphotericin B [3-5 mg/kg/day], followed by itraconazole [200 mg b.i.d.] | Deoxycholate amphotericin B [0.7-1 mg/kg/day], followed by itraconazole [200 mg b.i.d.] upon symptom resolution | Precise length of amphotericin B treatment varies. Suppressive treatment with itraconazole is necessary. |
Dissimated | Limposomal amphotericin B [3-5 mg/kg/day], followed by itraconazole [200 mg b.i.d.] | Deoxycholate amphotericin B [0.7-1 mg/kg/day], followed by itraconazole [200 mg b.i.d.] upon symptom resolution | Continue amphotericin B treatment until patient shows marked improvement for a minimum of 12 months. Suppressive treatment with itraconazole is necessary. |
Sporotrichosis in pregnant women | |||
Sporotrichosis in Children |