Paracoccidioidomycosis history and symptoms: Difference between revisions

Jump to navigation Jump to search
← Older editNewer edit →
VisualWikitext
Gerald Chi- (talk | contribs)
Bureaucrats, bureaucrats, nocaptcha, oversight, smwadministrator, Administrators, Widget editors
7,699 edits
mNo edit summary
Danitza Lukac (talk | contribs)
nocaptcha
762 edits
No edit summary
Line 3: Line 3:
{{PleaseHelp}}
{{PleaseHelp}}


==History and Symptoms==
==Overview==
Primary infection is thought to be autolimited and almost asymptomatic as [[histoplasmosis]] or Valley Fever. In young people, there is a progressive form of the disease (akin of tuberculous [[septicemia]] in tuberculous priminfection) with high prostrating fever, generalized [[lymphadenopathy]] and pulmonary involvement with milliary lesions. This juvenile form has a more severe prognosis even with treatment. The most common form is the so called adult form of paracoccidioidomycosis that is almost certainly a reactivation of the disease. Chronic PMC has mainly pulmonary symptoms. <ref> Paracoccidioidomycosis. Wikipedia.https://en.wikipedia.org/wiki/Paracoccidioidomycosis. Accessed on January 12, 2015</ref> <ref name=?>


Paracoccidioidomycosis is a [[systemic mycosis]] caused by the dimorphic fungus Paracoccidioides. It frequently involves [[mucous membrane]]s, [[lymph node]]s, bone and lungs and requires some degree of host [[immunosuppression]].
==History==
Paracoccidioidomycosis has been reported as an autochthonous disease, that tends to affect agriculture workers from southern Mexico to northern Argentina. Paracoccidioidomycosis is prevalent in Brazil, Colombia, Venezuela, and Argentina, and is classically associated with individuals from rural areas. Travellers that have been to endemic areas are in risk of contracting PMC as well as the endemics areas population. <ref> Paracoccidioidomycosis. Wikipedia.https://en.wikipedia.org/wiki/Paracoccidioidomycosis. Accessed on January 12, 2015</ref>


Primary infection is thought to be autolimited and almost asymptomatic as [[histoplasmosis]] or Valley Fever. In young people, there is a progressive form of the disease (akin of tuberculous [[septicemia]] in tuberculous priminfection) with high prostrating fever, generalized [[lymphadenopathy]] and pulmonary involvement with milliary lesions. This juvenile form has a more severe prognosis even with treatment. The most common form is the so called adult form of paracoccidioidomycosis that is almost certainly a reactivation of the disease.
==Symptoms==
Acute:
*Fever
*Lymph swelling
*Abdominal pain
*Weakness
*Weight loss
*Osteoarticular pain
*Osteoarticular tumefaction
*Skin lesions <ref name="aaa">Pereira R, Bucaretchi F, Barison E, Hessel G, Tresoldi A. Paracoccidioidomycosis in children: Clinical presentation, follow-up and outcome. ''Rev. Inst. Med. trop. S. Paulo.''2004;46(3):127-131. </ref>


Painful lesions with a violaceous hue in lips and oral mucosa are common as is cervical lymphadenitis teeming with polygemulating yeasts in the biopsy. In this form, differential diagnosis must be made with mucocutaneous [[leishmaniasis]], [[yaws]] and [[Tuberculosis|TB]].
Chronic:
 
*Dry cough
[[Pulmonary]] involvement is also common, it starts as [[lobar pneumonia]] or [[pleurisy]] but without remission at ninth day; the patient remains [[febrile]], [[cough]]s, [[loses weight]] and the [[X rays]] reveal milliary shadows throughout lung fields. Other organs can be involved, like bones, [[meninges]], arteries and [[spleen]] but this is very rare.
*Dyspnea
*Hemoptisis
*Sputum
*Dysphagia
*Asthenia
*Fever
*Skin lesions: mucose oropharynx ulcers
*Soreness
*Sialorrhea
*Odynophagia
*Cutaneous lesions: Erythematous ulcers (lip, tongue, palate, cheek, nose, larynx, penis, eyes) <ref name=g>Vignolles M, Melo V, Paniagua B, Giménez M,  Piccoli L. Paracoccidioidomicosis genital: localización infrecuente. ''Arch. Argent. Dermatol. ''2015;65(2):54-56</ref> <ref name="pmid10742725">{{cite journal| author=Severo LC, Kauer CL, Oliveira Fd, Rigatti RA, Hartmann AA, Londero AT| title=Paracoccidioidomycosis of the male genital tract. Report of eleven cases and a review of Brazilian literature. | journal=Rev Inst Med Trop Sao Paulo | year= 2000 | volume= 42 | issue= 1 | pages= 38-40 | pmid=10742725 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10742725  }} </ref> <ref name=o>Dawaher J, Colella MR, Rosello A, Perez C, Olaizola C, Newman W, Landaeta ME, Rangel L, Mata S. Paracoccidioidomicosis: clínica, epidemiología y tratamiento ''Kasmera''2012;40(2):142-185</ref> <ref name=a>Vargas J, Vargas R. Paracoccidioidomicosis. ''Rev. enferm. infecc. trop. ''2009;1(1):49-56</ref>


[[Image:Paracoccidioidomycosis-cara.jpg|thumb|none|This image from 1965 depicted a right anterior-oblique view of a Sao Paulo, Brazilian man’s face that displayed the severely-destructive cutaneous pathologic changes seen there, due of the mycotic infection, paracoccidioidomycosis. Symptoms involve ulcerations of the skin and mucous membranes of the mouth, nose and pharynx.<ref>Paracoccidioidomycosis. CDC Public Health Image Library (PHIL).http://phil.cdc.gov/phil/details.asp. Accessed on January 20, 2016</ref>]]
[[Image:Paracoccidioidomycosis-tongue.jpg|thumb|none|Captured prior to beginning any treatment, this image depicts an anterior view of a male patient’s open mouth, revealing the man’s tongue, which exhibited a lesion on its left lateral edge that proved to be a case of paracoccidioidomycosis.<ref>Paracoccidioidomycosis. CDC Public Health Image Library (PHIL).http://phil.cdc.gov/phil/details.asp. Accessed on January 20, 2016</ref>]]
[[Image:Paracoccidioidomycosis-niño.jpg|thumb|none|This image from 1965 depicted an anterior view of a Sao Paulo, Brazilian child’s face that displayed the ravages of the mycotic infection, paracoccidioidomycosis.<ref>Paracoccidioidomycosis. CDC Public Health Image Library (PHIL).http://phil.cdc.gov/phil/details.asp. Accessed on January 20, 2016</ref>]]
==References==
==References==
{{reflist|2}}
{{reflist|2}}

Revision as of 22:25, 20 January 2016

Paracoccidioidomycosis Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Paracoccidioidomycosis from other Diseases

Epidemiology and Demographics

Risk Factors

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Criteria

History and Symptoms

Physical Examination

Laboratory Findings

Imaging Findings

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Future or Investigational Therapies

Case Studies

Case #1

Paracoccidioidomycosis history and symptoms On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Paracoccidioidomycosis history and symptoms

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Paracoccidioidomycosis history and symptoms

CDC on Paracoccidioidomycosis history and symptoms

Paracoccidioidomycosis history and symptoms in the news

Blogs on Paracoccidioidomycosis history and symptoms

Directions to Hospitals Treating Paracoccidioidomycosis

Risk calculators and risk factors for Paracoccidioidomycosis history and symptoms

Please help WikiDoc by adding content here. It's easy! Click here to learn about editing.

Overview

Primary infection is thought to be autolimited and almost asymptomatic as histoplasmosis or Valley Fever. In young people, there is a progressive form of the disease (akin of tuberculous septicemia in tuberculous priminfection) with high prostrating fever, generalized lymphadenopathy and pulmonary involvement with milliary lesions. This juvenile form has a more severe prognosis even with treatment. The most common form is the so called adult form of paracoccidioidomycosis that is almost certainly a reactivation of the disease. Chronic PMC has mainly pulmonary symptoms. [1] Closing </ref> missing for <ref> tag

Symptoms

Acute:

  • Fever
  • Lymph swelling
  • Abdominal pain
  • Weakness
  • Weight loss
  • Osteoarticular pain
  • Osteoarticular tumefaction
  • Skin lesions [2]

Chronic:

  • Dry cough
  • Dyspnea
  • Hemoptisis
  • Sputum
  • Dysphagia
  • Asthenia
  • Fever
  • Skin lesions: mucose oropharynx ulcers
  • Soreness
  • Sialorrhea
  • Odynophagia
  • Cutaneous lesions: Erythematous ulcers (lip, tongue, palate, cheek, nose, larynx, penis, eyes) [3] [4] [5] [6]
This image from 1965 depicted a right anterior-oblique view of a Sao Paulo, Brazilian man’s face that displayed the severely-destructive cutaneous pathologic changes seen there, due of the mycotic infection, paracoccidioidomycosis. Symptoms involve ulcerations of the skin and mucous membranes of the mouth, nose and pharynx.[7]
Captured prior to beginning any treatment, this image depicts an anterior view of a male patient’s open mouth, revealing the man’s tongue, which exhibited a lesion on its left lateral edge that proved to be a case of paracoccidioidomycosis.[8]
This image from 1965 depicted an anterior view of a Sao Paulo, Brazilian child’s face that displayed the ravages of the mycotic infection, paracoccidioidomycosis.[9]

References

  1. ↑ Paracoccidioidomycosis. Wikipedia.https://en.wikipedia.org/wiki/Paracoccidioidomycosis. Accessed on January 12, 2015
  2. ↑ Pereira R, Bucaretchi F, Barison E, Hessel G, Tresoldi A. Paracoccidioidomycosis in children: Clinical presentation, follow-up and outcome. Rev. Inst. Med. trop. S. Paulo.2004;46(3):127-131.
  3. ↑ Vignolles M, Melo V, Paniagua B, Giménez M, Piccoli L. Paracoccidioidomicosis genital: localización infrecuente. Arch. Argent. Dermatol. 2015;65(2):54-56
  4. ↑ Severo LC, Kauer CL, Oliveira Fd, Rigatti RA, Hartmann AA, Londero AT (2000). "Paracoccidioidomycosis of the male genital tract. Report of eleven cases and a review of Brazilian literature". Rev Inst Med Trop Sao Paulo. 42 (1): 38–40. PMID 10742725.
  5. ↑ Dawaher J, Colella MR, Rosello A, Perez C, Olaizola C, Newman W, Landaeta ME, Rangel L, Mata S. Paracoccidioidomicosis: clínica, epidemiología y tratamiento Kasmera2012;40(2):142-185
  6. ↑ Vargas J, Vargas R. Paracoccidioidomicosis. Rev. enferm. infecc. trop. 2009;1(1):49-56
  7. ↑ Paracoccidioidomycosis. CDC Public Health Image Library (PHIL).http://phil.cdc.gov/phil/details.asp. Accessed on January 20, 2016
  8. ↑ Paracoccidioidomycosis. CDC Public Health Image Library (PHIL).http://phil.cdc.gov/phil/details.asp. Accessed on January 20, 2016
  9. ↑ Paracoccidioidomycosis. CDC Public Health Image Library (PHIL).http://phil.cdc.gov/phil/details.asp. Accessed on January 20, 2016
Retrieved from "https://www.wikidoc.org/index.php?title=Paracoccidioidomycosis_history_and_symptoms&oldid=1204436"