Neoplastic meningitis natural history, complications and prognosis: Difference between revisions
Jump to navigation
Jump to search
| Line 11: | Line 11: | ||
Complications of neoplastic meningitis include:<ref name=dcomplicationsnm1>Complications of leptomeningitis. Dr Amir Rezaee and A.Prof Frank Gaillard et al. Radiopaedia 2016. http://radiopaedia.org/articles/leptomeningitis. Accessed on January 21, 2016</ref> | Complications of neoplastic meningitis include:<ref name=dcomplicationsnm1>Complications of leptomeningitis. Dr Amir Rezaee and A.Prof Frank Gaillard et al. Radiopaedia 2016. http://radiopaedia.org/articles/leptomeningitis. Accessed on January 21, 2016</ref> | ||
*[[Hydrocephalus]] | *[[Hydrocephalus]] | ||
*[[Encephalopathy]] | |||
*[[empyema|Subdural empyema]] | *[[empyema|Subdural empyema]] | ||
*[[empyema|Epidural empyema]] | *[[empyema|Epidural empyema]] | ||
Revision as of 15:04, 22 January 2016
|
Neoplastic meningitis Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Case Studies |
|
Neoplastic meningitis natural history, complications and prognosis On the Web |
|
American Roentgen Ray Society Images of Neoplastic meningitis natural history, complications and prognosis |
|
FDA on Neoplastic meningitis natural history, complications and prognosis |
|
CDC on Neoplastic meningitis natural history, complications and prognosis |
|
Neoplastic meningitis natural history, complications and prognosis in the news |
|
Blogs on Neoplastic meningitis natural history, complications and prognosis |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2]
Overview
Natural History
- Neoplastic meningitis has a widely disseminated and progressive presentation.
Complications
Complications of neoplastic meningitis include:[1]
- Hydrocephalus
- Encephalopathy
- Subdural empyema
- Epidural empyema
- Cerebritis
- Cerebral abscess
- Stroke
- Ventriculitis
- Dural sinus thrombosis
Prognosis
- The median survival time of patients without treatment of neoplastic meningitis is 4-6 weeks.[2]
- Neoplastic meningitis due to breast cancer has the best prognosis, where the median survival time is approximately 6 months after diagnosis.[2]
- Poor prognostic factors for neoplastic meningitis include:[2]
- Negative hormone receptor status
- Poor performance status
- Multiple fixed neurological deficits
- Coexistent carcinomatous encephalopathy
- More than 3 chemotherapy regimes
- High Cyfra 21-1 level at diagnosis
- Cyfra 21-1 is a fragment of the cytokeratin-19 and may reflect the tumor burden within the cerebrospinal fluid.
References
- ↑ Complications of leptomeningitis. Dr Amir Rezaee and A.Prof Frank Gaillard et al. Radiopaedia 2016. http://radiopaedia.org/articles/leptomeningitis. Accessed on January 21, 2016
- ↑ 2.0 2.1 2.2 Prognosis of neoplastic meningitis. Wikipedia 2016. https://en.wikipedia.org/wiki/Neoplastic_meningitis. Accessed on January 20, 2016