Neoplastic meningitis medical therapy: Difference between revisions
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{{familytree/start |summary=Treatment of neoplastic meningitis}} | {{familytree/start |summary=Treatment of neoplastic meningitis}} | ||
{{familytree |boxstyle=background: #DCDCDC;| | | | | | | | | | | A01 | | | | | | | | | | | | | |A01=<div style="width: 12em; padding:0.2em;">'''Treatment of neoplastic meningitis'''</div>}} | {{familytree |boxstyle=background: #DCDCDC;| | | | | | | | | | | | | A01| | | | | | | | | | | | | |A01=<div style="width: 12em; padding:0.2em;">'''Treatment of neoplastic meningitis'''</div>}} | ||
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{{familytree |boxstyle=background: #DCDCDC;| | | | | | B01 | | | | {{familytree |boxstyle=background: #DCDCDC;| | | | | | | B01 | | B02 | | B03 | | B04 | | | | | | | | | | | | | |B01=<div style="width: 9em; padding:0.2em;">'''Intrathecal<br>chemotherapy<br>''' </div>|B02=<div style="width: 9em; padding:0.2em;">'''Radiotherapy'''</div>|B03=<div style="width: 9em; padding:0.2em;">'''Surgery'''</div>||B04=<div style="width: 9em; padding:0.2em;">'''Supportive care'''</div>}} | ||
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:*[[Thiotepa]] | :*[[Thiotepa]] | ||
===Radiotherapy=== | |||
===Supportive Care=== | |||
Supportive care should be directed towards all patients with neoplastic meningitis, regardless of the t | |||
==References== | ==References== | ||
Revision as of 22:04, 22 January 2016
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Neoplastic meningitis Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
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Neoplastic meningitis medical therapy On the Web |
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American Roentgen Ray Society Images of Neoplastic meningitis medical therapy |
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Risk calculators and risk factors for Neoplastic meningitis medical therapy |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2]
Overview
The mainstay of therapy for neoplastic meningitis is intrathecal chemotherapy.[1]
Medical Therapy
The various treatment options for neoplastic meningitis include:[1]
Treatment of neoplastic meningitis | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Intrathecal chemotherapy | Radiotherapy | Surgery | Supportive care | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Chemotherapy
- The mainstay of therapy for neoplastic meningitis is intrathecal chemotherapy.[1]
- Chemotherapy can help in treatment of the total involved neuraxis. It may be administered systemically or intrathecally.
- Chemotherapy given via systemic route has poor CSF penetration, hence intrathecal chemotherapy is the preferred mode of administration.
- Chemotherapeutic drugs can be given intrathecally either by lumbar puncture or via an intraventricular reservoir system.
- Accessing via the intraventricular reservoir system is preferred to lumbar puncture for the following reasons:[1]
- Simple procedure
- More comfortable for the patient
- Safer than repeated lumbar punctures
- Better uniform distribution of the drug in the subarachnoid space
- Chemotherapeutic agents that are routinely used include:[1]
Radiotherapy
Supportive Care
Supportive care should be directed towards all patients with neoplastic meningitis, regardless of the t