Adult T-cell leukemia laboratory findings: Difference between revisions
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* Detect [[antibodies]] present against [[HTLV]] [[antigen]]s | * Detect [[antibodies]] present against [[HTLV]] [[antigen]]s | ||
===Immunohistochemistry=== | ===Immunohistochemistry=== | ||
* Adult T-cell leukemia cells are typically [[CD2]], [[CD4]], [[CD5]], and [[CD8]] positive. | * Adult T-cell leukemia cells are typically [[CD2]], [[CD4]], [[CD5]], and [[CD8]] positive. | ||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
Revision as of 14:43, 25 January 2016
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Haytham Allaham, M.D. [2]
Overview
Laboratory findings consistent with the diagnosis of adult T-cell leukemia include abnormal anemia, thrombocytopenia, and elevated lymphocyte count. Hypercalcemia is a key feature among patients with adult T-cell leukemia leukemia.
Laboratory Findings
Complete Blood Count
- Anemia
- Thrombocytopenia
- Elevated lymphocyte count
Basic Metabolic Panel
Peripheral Smear
- Charecterstic leukemia cells with sharp nuclear indentations and a prominent nucleoli
- "Cloverleaf" or "flower" cells
Antibody Titres
- Detect antibodies present against HTLV antigens