Human parainfluenza virus: Difference between revisions
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*Human parainfluenza viruses (HPIVs) are a group of four [[serotypes]] of enveloped, single stranded negative sense [[RNA]] viruses.<ref name = "ParaChar">{{cite journal |vauthors=Vainionpää R, Hyypiä T |title=Biology of parainfluenza viruses |journal=Clin. Microbiol. Rev. |volume=7 |issue=2 |pages=265–75 |year=1994 |pmid=8055470 |pmc=358320 |doi= |url=}}</ref> | *Human parainfluenza viruses (HPIVs) are a group of four [[serotypes]] of enveloped, single stranded negative sense [[RNA]] viruses.<ref name = "ParaChar">{{cite journal |vauthors=Vainionpää R, Hyypiä T |title=Biology of parainfluenza viruses |journal=Clin. Microbiol. Rev. |volume=7 |issue=2 |pages=265–75 |year=1994 |pmid=8055470 |pmc=358320 |doi= |url=}}</ref> | ||
*The human parainfluenza virus [[genome]] consists of approximately 15,000 [[nucleotides]] used to encode the following six structural proteins:.<ref name="Henrickson2003">{{cite journal|last1=Henrickson|first1=K. J.|title=Parainfluenza Viruses|journal=Clinical Microbiology Reviews|volume=16|issue=2|year=2003|pages=242–264|issn=0893-8512|doi=10.1128/CMR.16.2.242-264.2003}}</ref> | *The human parainfluenza virus [[genome]] consists of approximately 15,000 [[nucleotides]] used to encode the following six structural proteins:.<ref name="Henrickson2003">{{cite journal|last1=Henrickson|first1=K. J.|title=Parainfluenza Viruses|journal=Clinical Microbiology Reviews|volume=16|issue=2|year=2003|pages=242–264|issn=0893-8512|doi=10.1128/CMR.16.2.242-264.2003}}</ref> | ||
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Revision as of 17:23, 27 January 2016
Croup Microchapters |
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Human parainfluenza virus On the Web |
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Human parainfluenza virus | ||||||
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A Transmission Electron Micrograph (TEM) depicting parainfluenza virions, and free filamentous nucleocapsid material.
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Virus classification | ||||||
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This page is about microbiologic aspects of the organism(s). For clinical aspects of the disease, see Croup.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Luke Rusowicz-Orazem, B.S.
Overview
Microbiological Characteristics
- Human parainfluenza viruses (HPIVs) are a group of four serotypes of enveloped, single stranded negative sense RNA viruses.[1]
- The human parainfluenza virus genome consists of approximately 15,000 nucleotides used to encode the following six structural proteins:.[2]
Protein | Location | Function |
---|---|---|
hemagglutinin | Envelope | Attachment and cell entry |
fusion protein | Envelope | Fusion and cell entry |
matrix protein | Within the envelope | Assembly |
nucleoprotein | Nucleocapsid | Forms a complex with the RNA genome |
phosphoprotein | Nucleocapsid | Forms as a part of the RNA polymerase complex |
large protein | Nucleocapsid | Forms as a part of the RNA polymerase complex |