Human parainfluenza virus: Difference between revisions
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==Microbiological Characteristics== | ==Microbiological Characteristics== | ||
*Human parainfluenza | *Human parainfluenza virus (HPIV) is an enveloped, single stranded negative sense [[RNA]] virus.<ref name = "ParaChar">{{cite journal |vauthors=Vainionpää R, Hyypiä T |title=Biology of parainfluenza viruses |journal=Clin. Microbiol. Rev. |volume=7 |issue=2 |pages=265–75 |year=1994 |pmid=8055470 |pmc=358320 |doi= |url=}}</ref> | ||
*Human parainfluenza virus is comprised of four distinct [[serotypes]]:<ref name ="CroupType">{{cite book | last = Baron | first = Samuel | title = Medical microbiology | publisher = University of Texas Medical Branch at Galveston | location = Galveston, Tex | year = 1996 | isbn = 0-9631172-1-1 }}</ref> | |||
**HPIV-1 | |||
**HPIV-2 | |||
**HPIV-3 | |||
**HPIV-4 | |||
*The human parainfluenza virus [[genome]] consists of approximately 15,000 [[nucleotides]] used to encode the following six structural proteins:.<ref name="Henrickson2003">{{cite journal|last1=Henrickson|first1=K. J.|title=Parainfluenza Viruses|journal=Clinical Microbiology Reviews|volume=16|issue=2|year=2003|pages=242–264|issn=0893-8512|doi=10.1128/CMR.16.2.242-264.2003}}</ref> | *The human parainfluenza virus [[genome]] consists of approximately 15,000 [[nucleotides]] used to encode the following six structural proteins:.<ref name="Henrickson2003">{{cite journal|last1=Henrickson|first1=K. J.|title=Parainfluenza Viruses|journal=Clinical Microbiology Reviews|volume=16|issue=2|year=2003|pages=242–264|issn=0893-8512|doi=10.1128/CMR.16.2.242-264.2003}}</ref> | ||
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**[[Respirovirus]]: HPIV-1 & HPIV-3 | **[[Respirovirus]]: HPIV-1 & HPIV-3 | ||
**[[Rubulavirus]]: HPIV-2 & HPIV-4 | **[[Rubulavirus]]: HPIV-2 & HPIV-4 | ||
==Transmission== | |||
*Human parainfluenza virus is primarily transmitted by the following:<ref name="urlHuman Parainfluenza Viruses | Transmission of HPIVs | CDC">{{cite web |url=http://www.cdc.gov/parainfluenza/about/transmission.html |title=Human Parainfluenza Viruses | Transmission of HPIVs | CDC |format= |work= |accessdate=}}</ref> | |||
**Airborne respiratory droplets from coughing and sneezing | |||
**Close physical contact with an infected individual | |||
**Physical contact with a contaminated surface | |||
==References== | ==References== | ||
Revision as of 17:59, 27 January 2016
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Croup Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
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Human parainfluenza virus On the Web |
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American Roentgen Ray Society Images of Human parainfluenza virus |
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Risk calculators and risk factors for Human parainfluenza virus |
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 A Transmission Electron Micrograph (TEM) depicting parainfluenza virions, and free filamentous nucleocapsid material.
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This page is about microbiologic aspects of the organism(s). For clinical aspects of the disease, see Croup.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Luke Rusowicz-Orazem, B.S.
Overview
Microbiological Characteristics
- The human parainfluenza virus genome consists of approximately 15,000 nucleotides used to encode the following six structural proteins:.[3]
| Protein | Location | Function |
|---|---|---|
| hemagglutinin | Envelope | Attachment and cell entry |
| fusion protein | Envelope | Fusion and cell entry |
| matrix protein | Within the envelope | Assembly |
| nucleoprotein | Nucleocapsid | Forms a complex with the RNA genome |
| phosphoprotein | Nucleocapsid | Forms as a part of the RNA polymerase complex |
| large protein | Nucleocapsid | Forms as a part of the RNA polymerase complex |
- Human parainfluenza virus is a member of the paramyxoviridae family.
- The genus for human parainfluenza virus depends on its serotype:[3]
- Respirovirus: HPIV-1 & HPIV-3
- Rubulavirus: HPIV-2 & HPIV-4
Transmission
- Human parainfluenza virus is primarily transmitted by the following:[4]
- Airborne respiratory droplets from coughing and sneezing
- Close physical contact with an infected individual
- Physical contact with a contaminated surface
References
- ↑ Vainionpää R, Hyypiä T (1994). "Biology of parainfluenza viruses". Clin. Microbiol. Rev. 7 (2): 265–75. PMC 358320. PMID 8055470.
- ↑ Baron, Samuel (1996). Medical microbiology. Galveston, Tex: University of Texas Medical Branch at Galveston. ISBN 0-9631172-1-1.
- ↑ 3.0 3.1 Henrickson, K. J. (2003). "Parainfluenza Viruses". Clinical Microbiology Reviews. 16 (2): 242–264. doi:10.1128/CMR.16.2.242-264.2003. ISSN 0893-8512.
- ↑ "Human Parainfluenza Viruses | Transmission of HPIVs | CDC".