MALT lymphoma natural history: Difference between revisions
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==Natural History== | ==Natural History== | ||
*Many people are diagnosed with localized or early stage disease that has not spread elsewhere in the body. MALT lymphoma is usually slow growing (indolent), but some can be high grade. They often remain in the area in which they started for a long period of time. Rarely, MALT lymphomas can change (transform) into a more aggressive large cell lymphoma. | *Many people are diagnosed with localized or early stage disease that has not spread elsewhere in the body. MALT lymphoma is usually slow growing (indolent), but some can be high grade. They often remain in the area in which they started for a long period of time. Rarely, MALT lymphomas can change (transform) into a more aggressive large cell lymphoma.<ref name=extranodalmarginalzoneofmucosaassociatedlymphoidtissueMALTlymphoma1>Extranodal marginal zone of mucosa-associated lymphoid tissue (MALT lymphoma). Canadian Cancer Society 2016. http://www.cancer.ca/en/cancer-information/cancer-type/non-hodgkin-lymphoma/non-hodgkin-lymphoma/types-of-nhl/malt-lymphoma/?region=on. Accessed on January 28, 2016</ref> | ||
==Prognosis== | ==Prognosis== | ||
Revision as of 20:23, 27 January 2016
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MALT lymphoma Microchapters |
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MALT lymphoma natural history On the Web |
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American Roentgen Ray Society Images of MALT lymphoma natural history |
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Risk calculators and risk factors for MALT lymphoma natural history |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2]
Overview
Natural History
- Many people are diagnosed with localized or early stage disease that has not spread elsewhere in the body. MALT lymphoma is usually slow growing (indolent), but some can be high grade. They often remain in the area in which they started for a long period of time. Rarely, MALT lymphomas can change (transform) into a more aggressive large cell lymphoma.[1]
Prognosis
- The prognosis is good, and the 10-year survival rate for gastric MALT lymphoma is approximately 90% with a disease-free survival of approximately 70%.[2]
- However, in rare instances, MALT lymphoma can progress and transform into aggressive high-grade tumors, such as extranodal diffuse large B cell lymphoma (eDLBCL), whereby the 10-year survival rate drops to approximately 42%.
References
- ↑ Extranodal marginal zone of mucosa-associated lymphoid tissue (MALT lymphoma). Canadian Cancer Society 2016. http://www.cancer.ca/en/cancer-information/cancer-type/non-hodgkin-lymphoma/non-hodgkin-lymphoma/types-of-nhl/malt-lymphoma/?region=on. Accessed on January 28, 2016
- ↑ Troppan, Katharina; Wenzl, Kerstin; Neumeister, Peter; Deutsch, Alexander (2015). "Molecular Pathogenesis of MALT Lymphoma". Gastroenterology Research and Practice. 2015: 1–10. doi:10.1155/2015/102656. ISSN 1687-6121.