Non small cell lung cancer overview: Difference between revisions
| Line 5: | Line 5: | ||
==Overview== | ==Overview== | ||
'''Non small cell lung carcinoma''' ('''NSCLC''') is any type of epithelial [[lung cancer]] other than [[small-cell lung carcinoma|small cell lung carcinoma]] (SCLC). NSCLC arises from the epithelial cells of the lung of the central bronchi to terminal alveoli. These tumors account for about 85% of all lung cancers.<ref>http://www.cancer. | '''Non-small cell lung carcinoma''' ('''NSCLC''') is any type of epithelial [[lung cancer]] other than [[small-cell lung carcinoma|small cell lung carcinoma]] (SCLC). NSCLC arises from the epithelial cells of the lung of the central bronchi to terminal alveoli. These tumors account for about 85% of all lung cancers. Non-small cell lung cancer may be classified according to the WHO histological classification system into 3 main types: squamous cell carcinoma, adenocarcinoma, and large cell carcinoma. Other less common subtypes, include: adenosquamous lung carcinoma, pulmonary sarcomatoid carcinoma, carcinoid tumors of lung, and carcinomas of the lung of salivary gland type.<ref name="NSCLC"> Non-Small Cell Lung Cancer Treatment –for health professionals. National Cancer Institute – Physician Data Query PDQ. http://www.cancer.gov/types/lung/hp/non-small-cell-lung-treatment-pdq#link/_361_toc Accessed on February 3, 2016.</ref> NSCLC tumors are relatively insensitive to [[chemotherapy]], compared to small cell carcinoma. When possible, they are primarily treated by surgical resection with curative intent, although chemotherapy is increasingly being used both pre-operatively ([[Neoadjuvant therapy|neoadjuvant chemotherapy]]) and post-operatively ([[Adjuvant therapy|adjuvant chemotherapy]]). | ||
==Historical Perspective== | ==Historical Perspective== | ||
Revision as of 14:38, 3 February 2016
|
Non Small Cell Lung Cancer Microchapters |
|
Differentiating Non Small Cell Lung Cancer from other Diseases |
|---|
|
Diagnosis |
|
Treatment |
|
Case Studies |
|
Non small cell lung cancer overview On the Web |
|
American Roentgen Ray Society Images of Non small cell lung cancer overview |
|
Directions to Hospitals Treating Non small cell carcinoma of the lung |
|
Risk calculators and risk factors for Non small cell lung cancer overview |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Maria Fernanda Villarreal, M.D. [2]
Overview
Non-small cell lung carcinoma (NSCLC) is any type of epithelial lung cancer other than small cell lung carcinoma (SCLC). NSCLC arises from the epithelial cells of the lung of the central bronchi to terminal alveoli. These tumors account for about 85% of all lung cancers. Non-small cell lung cancer may be classified according to the WHO histological classification system into 3 main types: squamous cell carcinoma, adenocarcinoma, and large cell carcinoma. Other less common subtypes, include: adenosquamous lung carcinoma, pulmonary sarcomatoid carcinoma, carcinoid tumors of lung, and carcinomas of the lung of salivary gland type.[1] NSCLC tumors are relatively insensitive to chemotherapy, compared to small cell carcinoma. When possible, they are primarily treated by surgical resection with curative intent, although chemotherapy is increasingly being used both pre-operatively (neoadjuvant chemotherapy) and post-operatively (adjuvant chemotherapy).
Historical Perspective
Non small cell lung cancer was first described by Thomas Venner of London in 1620.
Classification
Non-small cell lung cancer may be classified according to the WHO histological classification system into 3 main types: squamous cell carcinoma, adenocarcinoma, and large cell carcinoma. Other less common subtypes, include: adenosquamous lung carcinoma, pulmonary sarcomatoid carcinoma, carcinoid tumors of lung, and carcinomas of the lung of salivary gland type.[1]
Pathophysiology
Causes
Differentiating Non Small Cell Carcinoma of the Lung from other Diseases
Epidemiology and Demographics
Risk Factors
Screening
Natural History, Complications and Prognosis
Diagnosis
Staging
History and Symptoms
Physical Examination
Laboratory Findings
CT
MRI
Other Imaging Findings
Other Diagnostic Studies
Treatment
Medical Therapy
Surgery
References
- ↑ 1.0 1.1 Non-Small Cell Lung Cancer Treatment –for health professionals. National Cancer Institute – Physician Data Query PDQ. http://www.cancer.gov/types/lung/hp/non-small-cell-lung-treatment-pdq#link/_361_toc Accessed on February 3, 2016.