Non small cell lung cancer classification: Difference between revisions
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==Classification== | ==Classification== | ||
{| class="wikitable" | |||
! colspan="3" style="text-align: center; font-weight: bold;" | WHO histological classification system | |||
|- | |||
| style="text-align: center; font-weight: bold;" | Main types | |||
| style="text-align: center; font-weight: bold;" | Subtypes | |||
| style="text-align: center; font-weight: bold;" | Prevalence | |||
|- | |||
| Adenocarcinoma | |||
| | |||
*Adenocarcinoma, mixed | |||
*Acinar adenocarcinoma | |||
*Papillary adenocarcinoma | |||
*Bronchioloalveolar carcinoma | |||
*Nonmucinous | |||
*Mucinous | |||
*Mixed nonmucinous and mucinous or indeterminate | |||
*Solid adenocarcinoma with mucin production | |||
*Fetal adenocarcinoma | |||
*Mucinous (“colloid”) carcinoma | |||
*Mucinous cystadenocarcinoma | |||
*Signet ring adenocarcinoma | |||
*Clear cell adenocarcinoma | |||
| 40% of lung cancers | |||
|- | |||
| Squamous cell carcinoma | |||
| | |||
*Papillary | |||
*Clear cell | |||
*Small cell | |||
*Basaloid | |||
| 25% of lung cancers | |||
|- | |||
| Large cell carcinoma | |||
| | |||
*Large cell neuroendocrine carcinoma | |||
*Basaloid carcinoma | |||
*Lymphoepithelioma-like carcinoma | |||
*Clear cell carcinoma | |||
*Large cell carcinoma with rhabdoid phenotype | |||
| 10% of lung cancer | |||
|- | |||
| style="font-weight: bold;" | Less common types | |||
| | |||
| | |||
|- | |||
| Adenosquamous carcinoma | |||
| | |||
*No subtypes | |||
| Less than 5% | |||
|- | |||
| Sarcomatoid carcinoma | |||
| | |||
*Pleomorphic carcinoma | |||
*Spindle cell carcinoma | |||
*Giant cell carcinoma | |||
*Carcinosarcoma | |||
*Pulmonary blastoma | |||
| Less than 5% | |||
|- | |||
| Carcinoid tumor | |||
| | |||
*Typical carcinoid | |||
*Atypical carcinoid | |||
| Less than 5% | |||
|- | |||
| Salivary gland tumor | |||
| | |||
*Mucoepidermoid carcinoma | |||
*Adenoid cystic carcinoma | |||
*Epithelial-myoepithelial carcinoma | |||
| Less than 5% | |||
|} | |||
* The most common type of lung cancer is non–small cell lung cancer (NSCLC). About 85%–90% of all lung cancers are non–small cell lung cancer. The other 10%–15% are small cell lung cancer. | * The most common type of lung cancer is non–small cell lung cancer (NSCLC). About 85%–90% of all lung cancers are non–small cell lung cancer. The other 10%–15% are small cell lung cancer. | ||
Revision as of 15:18, 4 February 2016
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Non Small Cell Lung Cancer Microchapters |
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Differentiating Non Small Cell Lung Cancer from other Diseases |
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Risk calculators and risk factors for Non small cell lung cancer classification |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Shanshan Cen, M.D. [2]
Overview
Non-small cell lung cancer may be classified according to the WHO histological classification system into 3 main types: squamous cell carcinoma, adenocarcinoma, and large cell carcinoma. Other less common subtypes, include: adenosquamous lung carcinoma, pulmonary sarcomatoid carcinoma, carcinoid tumors of lung, and carcinomas of the lung of salivary gland type.[1]
Classification
| WHO histological classification system | ||
|---|---|---|
| Main types | Subtypes | Prevalence |
| Adenocarcinoma |
|
40% of lung cancers |
| Squamous cell carcinoma |
|
25% of lung cancers |
| Large cell carcinoma |
|
10% of lung cancer |
| Less common types | ||
| Adenosquamous carcinoma |
|
Less than 5% |
| Sarcomatoid carcinoma |
|
Less than 5% |
| Carcinoid tumor |
|
Less than 5% |
| Salivary gland tumor |
|
Less than 5% |
- The most common type of lung cancer is non–small cell lung cancer (NSCLC). About 85%–90% of all lung cancers are non–small cell lung cancer. The other 10%–15% are small cell lung cancer.
- There are 3 main types of non–small cell lung cancer: adenocarcinoma, squamous cell carcinoma and large cell carcinoma.
- Adenocarcinoma, mixed subtype
- Acinar adenocarcinoma
- Papillary adenocarcinoma
- Nonmucinous
- Mucinous
- Mixed nonmucinous and mucinous or indeterminate
- Solid adenocarcinoma with mucin production
- Fetal adenocarcinoma
- Mucinous (“colloid”) carcinoma
- Signet ring adenocarcinoma
- Clear cell adenocarcinoma
- Papillary
- Clear cell
- Small cell
- Basaloid
- Large cell neuroendocrine carcinoma
- Basaloid carcinoma
- Lymphoepithelioma-like carcinoma
- Clear cell carcinoma
- Large cell carcinoma with rhabdoid phenotype
- Adenosquamous carcinoma
- Pleomorphic carcinoma
- Spindle cell carcinoma
- Giant cell carcinoma
- Carcinoid tumor
- Typical carcinoid
- Atypical carcinoid
- Epithelial-myoepithelial carcinoma
References
- ↑ Non-Small Cell Lung Cancer Treatment –for health professionals. National Cancer Institute – Physician Data Query PDQ. http://www.cancer.gov/types/lung/hp/non-small-cell-lung-treatment-pdq#link/_361_toc Accessed on February 3, 2016.
- ↑ Travis, William (2004). Pathology and genetics of tumours of the lung, pleura, thymus, and heart. Lyon: IARC Press. ISBN 9283224183.
- ↑ Raz DJ, He B, Rosell R, Jablons DM (2006). "Bronchioloalveolar carcinoma: a review". Clin Lung Cancer. 7 (5): 313–22. doi:10.3816/CLC.2006.n.012. PMID 16640802.