Tick-borne encephalitis laboratory findings: Difference between revisions
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Created page with "__NOTOC__ {{CMG}} {{AE}} {{IMD}} {{Tick-borne encephalitis}} ==Overview== ==Laboratory findings== *Real-time polymerase chain reactions and other viral isolation techniques..." |
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==Laboratory findings== | ==Laboratory findings== | ||
*Real-time polymerase chain reactions and other viral isolation techniques in mammalian cell cultures may be used to identify a tick-borne encephalitis infection during the | ===Polymerase chain reaction=== | ||
*Immunofluorescence assays, immunoassays, IgM and IgG titers, as well as other serologic testing techniques may all be helpful in diagnosing an infection | *Real-time polymerase chain reactions and other viral isolation techniques in mammalian cell cultures may be used to identify a tick-borne encephalitis infection during the initial, viremic phase. | ||
*These methods are considered slightly inferior since a patient is less likely to seek medical attention prior to neurological manifestations when these methods are most effective. | |||
*Polymerase chain reaction is a key element of differential diagnose when testing for tick-borne encephalitis. | |||
*An RT-PCR for a differential diagnoses should be taken within the transient viremia stage, which occurs during the first week of the infection. | |||
*If examined and confirmed early in the infection, a patient may receive quicker treatment. | |||
*An early detection and treatment, as a result of a successful RT-PCR, may result in a higher survival rate and lessened complications due to infection. | |||
*RT-PCR is also a better method in individuals suffering from immediate onset of severe infection as well as those who have not yet produced any subsequent antibodies. | |||
===Serologic testing=== | |||
*Immunofluorescence assays, immunoassays, IgM and IgG titers, as well as other serologic testing techniques may all be helpful in diagnosing an infection. | |||
*Diagnosis is primarily determined according to this method. | |||
*An ELISA, or enzyme-linked immunosorbent assay, is commonly used as a method for diagnoses in later stages. | |||
*An ELISA is also considered the gold standard method in TBE diagnostic testing. | |||
==References== | |||
{{Reflist|2}} | |||
Revision as of 17:34, 4 February 2016
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Ilan Dock, B.S.
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Overview
Laboratory findings
Polymerase chain reaction
- Real-time polymerase chain reactions and other viral isolation techniques in mammalian cell cultures may be used to identify a tick-borne encephalitis infection during the initial, viremic phase.
- These methods are considered slightly inferior since a patient is less likely to seek medical attention prior to neurological manifestations when these methods are most effective.
- Polymerase chain reaction is a key element of differential diagnose when testing for tick-borne encephalitis.
- An RT-PCR for a differential diagnoses should be taken within the transient viremia stage, which occurs during the first week of the infection.
- If examined and confirmed early in the infection, a patient may receive quicker treatment.
- An early detection and treatment, as a result of a successful RT-PCR, may result in a higher survival rate and lessened complications due to infection.
- RT-PCR is also a better method in individuals suffering from immediate onset of severe infection as well as those who have not yet produced any subsequent antibodies.
Serologic testing
- Immunofluorescence assays, immunoassays, IgM and IgG titers, as well as other serologic testing techniques may all be helpful in diagnosing an infection.
- Diagnosis is primarily determined according to this method.
- An ELISA, or enzyme-linked immunosorbent assay, is commonly used as a method for diagnoses in later stages.
- An ELISA is also considered the gold standard method in TBE diagnostic testing.