Langerhans cell histiocytosis laboratory tests: Difference between revisions

	Langerhans cell histiocytosis Microchapters
Home
Patient Information
Overview
Historical Perspective
Classification
Pathophysiology
Causes
Differentiating Langerhans cell histiocytosis from other Diseases
Epidemiology and Demographics
Risk Factors
Screening
Natural History, Complications and Prognosis
Diagnosis
History and Symptoms
Physical Examination
Laboratory Findings
Chest X Ray
CT
MRI
Echocardiography or Ultrasound
Other Imaging Findings
Other Diagnostic Studies
Treatment
Medical Therapy
Surgery
Primary Prevention
Secondary Prevention
Cost-Effectiveness of Therapy
Future or Investigational Therapies
Case Studies
Case #1
Langerhans cell histiocytosis laboratory tests On the Web
Most recent articles
Most cited articles
Review articles
CME Programs
Powerpoint slides
Images
American Roentgen Ray Society Images of Langerhans cell histiocytosis laboratory tests All Images X-rays Echo & Ultrasound CT Images MRI
Ongoing Trials at Clinical Trials.gov
US National Guidelines Clearinghouse
NICE Guidance
FDA on Langerhans cell histiocytosis laboratory tests
on Langerhans cell histiocytosis laboratory tests
Langerhans cell histiocytosis laboratory tests in the news
Blogs on Langerhans cell histiocytosis laboratory tests
Directions to Hospitals Treating Langerhans cell histiocytosis
Risk calculators and risk factors for Langerhans cell histiocytosis laboratory tests

Revision as of 20:55, 4 February 2016

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Haytham Allaham, M.D. [2]

Diagnosis of LCH is confirmed histologically by tissue biopsy.
Haemotoxilin-eosin stain of biopsy slide will show features of Langerhans cell e.g. distinct cell margin, pink granular cytoplasm. Presence of Birbeck granules on electron microscopy and immuno-cytochemical features e. g. CD1 positivity are more specific.
Initially routine blood tests e.g. full blood count, liver function test, U&Es, bone profile are done to determine disease extent and rule out other causes.
Assessment of endocrine function and bone marrow biopsy are also performed when indicated.

@@ Line 12: / Line 12: @@
 ====Urinalysis====
 ====Immunohistochemistry====
 *Diagnosis of LCH is confirmed [[histologically]] by [[tissue]] [[biopsy]].
 *Haemotoxilin-eosin stain of biopsy slide will show features of Langerhans cell e.g. distinct cell margin, pink granular [[cytoplasm]]. Presence of [[Birbeck granules]] on [[electron microscopy]] and [[immuno-cytochemistry|immuno-cytochemical]] features e. g. [[CD1]] positivity are more specific.