Epithelioid sarcoma other diagnostic studies

Epithelioid sarcoma Microchapters
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]

Genetic Testing

• Loss of INI1 (also known as hSNF5 and SMARCB1) which is a member of SWI/SNF multi subunit chromatin remodeling complex located on the long arm of chromosome 22 (22q11.2) has been a diagnostic modalty of epithelioid sarcoma.

Immunohistochemistry

• Vimentin reactivity
• Pankeratin AE1/AE3 and epithelial membrane antigen
• Negative S100