Mucoepidermoid carcinoma pathophysiology: Difference between revisions

	Mucoepidermoid carcinoma Microchapters
Home
Patient Information
Overview
Historical Perspective
Classification
Pathophysiology
Causes
Differentiating Mucoepidermoid Carcinoma from other Diseases
Epidemiology and Demographics
Risk Factors
Natural History, Complications and Prognosis
Diagnosis
Staging
History and Symptoms
Physical Examination
Laboratory Findings
X Ray
CT
MRI
Ultrasound
Other Imaging Findings
Other Diagnostic Studies
Treatment
Medical Therapy
Surgery
Primary Prevention
Secondary Prevention
Cost-Effectiveness of Therapy
Future or Investigational Therapies
Case Studies
Case #1
Mucoepidermoid carcinoma pathophysiology On the Web
Most recent articles
Most cited articles
Review articles
CME Programs
Powerpoint slides
Images
American Roentgen Ray Society Images of Mucoepidermoid carcinoma pathophysiology All Images X-rays Echo and Ultrasound CT Images MRI
Ongoing Trials at Clinical Trials.gov
US National Guidelines Clearinghouse
NICE Guidance
FDA on Mucoepidermoid carcinoma pathophysiology
CDC on Mucoepidermoid carcinoma pathophysiology
Mucoepidermoid carcinoma pathophysiology in the news
Blogs on Mucoepidermoid carcinoma pathophysiology
Directions to Hospitals Treating Mucoepidermoid carcinoma
Risk calculators and risk factors for Mucoepidermoid carcinoma pathophysiology

← Older edit Newer edit →

VisualWikitext

Revision as of 16:55, 18 February 2016

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Mucoepidermoid carcinomas arise from mucous cells, which is normally involved in the secretion of mucous and the protection of surrounding tissue. The pathogenesis of mucoepidermoid carcinoma consists of abnormal production of mucin from mucous cells, associated with the aberrant overgrowth of squamous and epidermoid cells. Genes involved in the pathogenesis of mucoepidermoid carcinoma include MECT1 and MAML2 fusion genes. On gross pathology, mucoepidermoid carcinomas have a cystic, solid or mixed appearance, the tumor size ranges from 1 to 8 cm, and they are normally located on the parotid or submandibular gland .^[1] On microscopic histopathological analysis, mucoepidermoid carcinomas are characterized by mucous cells with abundant fluffy cytoplasm and large mucin vacuoles.^[1]

Pathophysiology

Microscopic Pathology

Mucicarmine staining is one stain used by pathologist for detection. ^[2]

Images

Histopathologic image of mucoepidermoid carcinoma of the major salivary gland. H & E stain.

Histopathologic image of mucoepidermoid carcinoma of the major salivary gland. The same lesion as shown in a filename "Mucoepidermoid carcinoma (2) HE stain.jpg". H & E stain.

Histopathologic image of mucoepidermoid carcinoma. Postoperative recurrence of the submandibular tumor. Alcian blue-PAS stain.

References

↑ ^1.0 ^1.1 Mucoepidermoid carcinoma. Libre Pathology. http://librepathology.org/wiki/index.php/Mucoepidermoid carcinoma Accessed on February 17, 2015
↑ http://www.nature.com/modpathol/journal/v13/n7/full/3880140a.html

Template:WikiDoc Sources

[libre-1] 1.0 ^1.1 Mucoepidermoid carcinoma. Libre Pathology. http://librepathology.org/wiki/index.php/Mucoepidermoid carcinoma Accessed on February 17, 2015

[2] ttp://www.nature.com/modpathol/journal/v13/n7/full/3880140a.html

[1]

[2]

@@ Line 1: / Line 1: @@
 __NOTOC__
-Please help WikiDoc by adding more content here.  It's easy!  Click  [[Help:How_to_Edit_a_Page|here]]  to learn about editing.
 {{Mucoepidermoid carcinoma}}
 {{CMG}}
 ==Overview==
+Mucoepidermoid carcinomas arise from mucous cells, which is normally involved in the secretion of mucous and the protection of surrounding [[tissue]].
+The pathogenesis of mucoepidermoid carcinoma consists of abnormal production of mucin from mucous cells, associated with the aberrant overgrowth of squamous and [[epidermoid cells]]. [[Genes]] involved in the [[pathogenesis]] of mucoepidermoid carcinoma include MECT1 and MAML2 fusion genes. On gross pathology, mucoepidermoid carcinomas have a cystic, solid or mixed appearance, the tumor size ranges from 1 to 8 cm, and they are normally located on the parotid or submandibular gland .<ref name="libre"> Mucoepidermoid carcinoma. Libre Pathology. http://librepathology.org/wiki/index.php/Mucoepidermoid carcinoma Accessed on February 17, 2015</ref> On microscopic histopathological analysis, mucoepidermoid carcinomas are characterized by mucous cells with abundant fluffy cytoplasm and large mucin vacuoles.<ref name="libre"> Mucoepidermoid carcinoma. Libre Pathology. http://librepathology.org/wiki/index.php/Mucoepidermoid carcinoma Accessed on February 17, 2015</ref>
 ==Pathophysiology==
 ===Microscopic Pathology===
@@ Line 23: / Line 26: @@
 [[Category:Types of cancer]]
 [[Category:Oral pathology]]
-[[Category:Needs content]]
 {{WikiDoc Help Menu}}
 {{WikiDoc Sources}}