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__NOTOC__ | __NOTOC__ | ||
{{Non small cell lung cancer}} | {{Non small cell lung cancer}} | ||
{{CMG}}; {{AE}} {{SC}} | {{CMG}}; {{AE}} {{SC}} {{MV}} | ||
==Overview== | ==Overview== | ||
If left untreated, patients with non-small cell lung cancer may progress to develop metastases to adjacent lymph nodes or distant organ metastases to liver, bones (spine), or brain. Common complications of non-small cell lung cancer include malignant pleural effusion, acute respiratory failure, and pneumonia. Prognosis is generally regarded as poor with an all-stage average survival rate of 50%. The 5-year recurrence rate of non-small cell lung cancer is 24%.<ref name="pmid17356101">{{cite journal |vauthors=Soares M, Darmon M, Salluh JI, Ferreira CG, Thiéry G, Schlemmer B, Spector N, Azoulay E |title=Prognosis of lung cancer patients with life-threatening complications |journal=Chest |volume=131 |issue=3 |pages=840–6 |year=2007 |pmid=17356101 |doi=10.1378/chest.06-2244 |url=}}</ref> | |||
==Natural History== | |||
* Most patients with non-small cell lung cancer are initially asymptomatic. | |||
* The symptoms of non-small cell lung cancer usually develop in the fourth and sixth decade of life, and initially patients complain of chronic cough, diaphoresis, and weight-loss. | |||
* If left untreated, patients with non-small cell lung cancer may develop malignant pleural effusion, acute respiratory failure, pneumonia, respiratory acidosis, and distant organ metastases. | |||
==Complications== | |||
*Common complications of non-small cell lung cancer, include: | |||
:*Acute respiratory failure | |||
:*[[Respiratory acidosis]] | |||
:*Malignant pleural effusion | |||
:*[[Metastases]] | |||
:*[[Pneumonia]] | |||
==Prognosis== | ==Prognosis== | ||
* Non-small cell lung cancer prognosis is generally regarded as poor, with an all-stage 5% survival rate of 52%. | |||
* The recurrence rate of non-small cell lung cancer is 24% | |||
* The prognosis for malignant transformation of non-small cell lung cancer will depend on the histological grade, such as: | |||
'''Non–small cell lung cancer survival rate by stage'''<ref>Lung cancer. Canadian Cancer Society 2015. http://www.cancer.ca/en/cancer-information/cancer-type/lung/prognosis-and-survival/survival-statistics/?region=ab </ref> | '''Non–small cell lung cancer survival rate by stage'''<ref>Lung cancer. Canadian Cancer Society 2015. http://www.cancer.ca/en/cancer-information/cancer-type/lung/prognosis-and-survival/survival-statistics/?region=ab </ref> | ||
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==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
[[Category:Types of cancer]] | [[Category:Types of cancer]] | ||
[[Category:Disease]] | [[Category:Disease]] | ||
Revision as of 21:30, 23 February 2016
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Shanshan Cen, M.D. [2] Maria Fernanda Villarreal, M.D. [3]
Overview
If left untreated, patients with non-small cell lung cancer may progress to develop metastases to adjacent lymph nodes or distant organ metastases to liver, bones (spine), or brain. Common complications of non-small cell lung cancer include malignant pleural effusion, acute respiratory failure, and pneumonia. Prognosis is generally regarded as poor with an all-stage average survival rate of 50%. The 5-year recurrence rate of non-small cell lung cancer is 24%.[1]
Natural History
- Most patients with non-small cell lung cancer are initially asymptomatic.
- The symptoms of non-small cell lung cancer usually develop in the fourth and sixth decade of life, and initially patients complain of chronic cough, diaphoresis, and weight-loss.
- If left untreated, patients with non-small cell lung cancer may develop malignant pleural effusion, acute respiratory failure, pneumonia, respiratory acidosis, and distant organ metastases.
Complications
- Common complications of non-small cell lung cancer, include:
- Acute respiratory failure
- Respiratory acidosis
- Malignant pleural effusion
- Metastases
- Pneumonia
Prognosis
- Non-small cell lung cancer prognosis is generally regarded as poor, with an all-stage 5% survival rate of 52%.
- The recurrence rate of non-small cell lung cancer is 24%
- The prognosis for malignant transformation of non-small cell lung cancer will depend on the histological grade, such as:
Non–small cell lung cancer survival rate by stage[2]
| Stage | 5-year survival rate |
|---|---|
| IA | 49% |
| IB | 45% |
| IIA | 30% |
| IIB | 31% |
| IIIA | 14% |
| IIIB | 5% |
| IV | 1% |
References
- ↑ Soares M, Darmon M, Salluh JI, Ferreira CG, Thiéry G, Schlemmer B, Spector N, Azoulay E (2007). "Prognosis of lung cancer patients with life-threatening complications". Chest. 131 (3): 840–6. doi:10.1378/chest.06-2244. PMID 17356101.
- ↑ Lung cancer. Canadian Cancer Society 2015. http://www.cancer.ca/en/cancer-information/cancer-type/lung/prognosis-and-survival/survival-statistics/?region=ab