Seminoma risk factors: Difference between revisions
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:*increased risk in the contralateral normally descended testis | :*increased risk in the contralateral normally descended testis | ||
*Previous tumor in contralateral testis | *Previous tumor in contralateral testis | ||
*Family history of [[testicular germ cell tumor]] | *Family history of [[germ cell tumor|testicular germ cell tumor]] | ||
:*4x increased risk if father affected | :*4x increased risk if father affected | ||
:*9x increased risk if brother affected | :*9x increased risk if brother affected | ||
*Testicular | *Testicular microlithiasis | ||
:*8x increased risk in symptomatic testicle with microlithiasis | |||
no increased risk found in asymptomatic testicles therefore screening is unlikely to be useful | :*no increased risk found in asymptomatic testicles therefore screening is unlikely to be useful | ||
*Testicular dysgenesis | |||
:*Testicular feminization | |||
:*[[Klinefelter syndrome]] | |||
Klinefelter syndrome | *Other risk factors may include | ||
:*Infections such as [[HIV]], [[orchitis]] | |||
:*History of trauma | |||
:*Organ transplant immunosuppression | |||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
Revision as of 15:10, 25 February 2016
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Seminoma Microchapters |
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Seminoma risk factors On the Web |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2]
Overview
Risk Factors
Common risk factors for testicular seminoma include:[1][2]
- Caucasian race
- Undescended testis
- 10-40x increased risk
- around 10% of seminoma are associated with undescended testis
- higher risk if intra-abdominal testis compared with intra-inguinal
- orchidopexy prior to puberty can reduce the tumor risk
- increased risk in the contralateral normally descended testis
- Previous tumor in contralateral testis
- Family history of testicular germ cell tumor
- 4x increased risk if father affected
- 9x increased risk if brother affected
- Testicular microlithiasis
- 8x increased risk in symptomatic testicle with microlithiasis
- no increased risk found in asymptomatic testicles therefore screening is unlikely to be useful
- Testicular dysgenesis
- Testicular feminization
- Klinefelter syndrome
- Other risk factors may include
References
- ↑ Risk factors for testicular seminoma. Dr Marcin Czarniecki and Dr Andrew Dixon et al. Radiopaedia 2016. http://radiopaedia.org/articles/testicular-seminoma-1. Accessed on February 25, 2016>
- ↑ Risk factors for testicular germ cell tumors. Dr Matt A. Morgan and Dr Andrew Dixon et al. Radiopaedia 2016. Accessed on February 25, 2016